Comparing chronic obstructive pulmonary disease and depressive disorder in terms of inflammation-related biomarkers
Introduction Chronic obstructive pulmonary disease (COPD) is characterized by the presence of depressive symptoms. Material and methods Cytokine and deiodinase iodothyronines (DIOs) levels were evaluated in COPD patients and patients diagnosed with depressive disorder and control individuals. using...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Termedia Publishing House
2023-05-01
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| Series: | Archives of Medical Science |
| Subjects: | |
| Online Access: | https://www.archivesofmedicalscience.com/Comparing-chronic-obstructive-pulmonary-disease-and-depressive-disorder-in-terms,161803,0,2.html |
| _version_ | 1797435367945666560 |
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| author | Elżbieta Małujło-Balcerska Kasper Sipowicz Tadeusz Pietras |
| author_facet | Elżbieta Małujło-Balcerska Kasper Sipowicz Tadeusz Pietras |
| author_sort | Elżbieta Małujło-Balcerska |
| collection | DOAJ |
| description | Introduction
Chronic obstructive pulmonary disease (COPD) is characterized by the presence of depressive symptoms.
Material and methods
Cytokine and deiodinase iodothyronines (DIOs) levels were evaluated in COPD patients and patients diagnosed with depressive disorder and control individuals. using enzyme-linked immunosorbent assays.
Results
Interleukin 1β (IL-1β), and tumor necrosis factor-a (TNF-a) levels were higher in COPD and depression patients than in control individuals. DIO2 were significantly lower in COPD and recurrent depressive disorder (rDD) patients than in controls.
Conclusions
Changes in the levels of IL-1β, TNF-a and DIO2 in COPD patients may explain the presence of depression in COPD patients. |
| first_indexed | 2024-03-09T10:47:12Z |
| format | Article |
| id | doaj.art-2ce76ab2dcf64ca89649c40756dff181 |
| institution | Directory Open Access Journal |
| issn | 1734-1922 1896-9151 |
| language | English |
| last_indexed | 2024-03-09T10:47:12Z |
| publishDate | 2023-05-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Archives of Medical Science |
| spelling | doaj.art-2ce76ab2dcf64ca89649c40756dff1812023-12-01T09:51:47ZengTermedia Publishing HouseArchives of Medical Science1734-19221896-91512023-05-0119381481910.5114/aoms/161803161803Comparing chronic obstructive pulmonary disease and depressive disorder in terms of inflammation-related biomarkersElżbieta Małujło-Balcerska0Kasper Sipowicz1Tadeusz Pietras2Department of Pneumonology, Medical University of Lodz, Lodz, PolandDepartment of Interdisciplinary Disability Studies, Maria Grzegorzewska University, Warsaw, PolandSecond Department of Psychiatry, Institute of Psychiatry and Neurology, Warsaw, PolandIntroduction Chronic obstructive pulmonary disease (COPD) is characterized by the presence of depressive symptoms. Material and methods Cytokine and deiodinase iodothyronines (DIOs) levels were evaluated in COPD patients and patients diagnosed with depressive disorder and control individuals. using enzyme-linked immunosorbent assays. Results Interleukin 1β (IL-1β), and tumor necrosis factor-a (TNF-a) levels were higher in COPD and depression patients than in control individuals. DIO2 were significantly lower in COPD and recurrent depressive disorder (rDD) patients than in controls. Conclusions Changes in the levels of IL-1β, TNF-a and DIO2 in COPD patients may explain the presence of depression in COPD patients.https://www.archivesofmedicalscience.com/Comparing-chronic-obstructive-pulmonary-disease-and-depressive-disorder-in-terms,161803,0,2.htmlcytokineschronic obstructive pulmonary diseasedepressive disorderdeiodinase iodothyronine |
| spellingShingle | Elżbieta Małujło-Balcerska Kasper Sipowicz Tadeusz Pietras Comparing chronic obstructive pulmonary disease and depressive disorder in terms of inflammation-related biomarkers Archives of Medical Science cytokines chronic obstructive pulmonary disease depressive disorder deiodinase iodothyronine |
| title | Comparing chronic obstructive pulmonary disease and depressive disorder in terms of inflammation-related biomarkers |
| title_full | Comparing chronic obstructive pulmonary disease and depressive disorder in terms of inflammation-related biomarkers |
| title_fullStr | Comparing chronic obstructive pulmonary disease and depressive disorder in terms of inflammation-related biomarkers |
| title_full_unstemmed | Comparing chronic obstructive pulmonary disease and depressive disorder in terms of inflammation-related biomarkers |
| title_short | Comparing chronic obstructive pulmonary disease and depressive disorder in terms of inflammation-related biomarkers |
| title_sort | comparing chronic obstructive pulmonary disease and depressive disorder in terms of inflammation related biomarkers |
| topic | cytokines chronic obstructive pulmonary disease depressive disorder deiodinase iodothyronine |
| url | https://www.archivesofmedicalscience.com/Comparing-chronic-obstructive-pulmonary-disease-and-depressive-disorder-in-terms,161803,0,2.html |
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