Type 2 Diabetes Mellitus remission eighteen months after Roux-en-Y gastric bypass.
ABSTRACT Objective: to evaluate the effectiveness of Roux-en-Y gastric bypass in improving the glycemic profile of obese patients with type 2 Diabetes Mellitus (DM2) after 18 months of follow-up. Methods: four hundred sixty-eight pacients with DM2 and BMI ≥35 were submitted to Roux-en-Y gastric...
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| Format: | Article |
| Language: | English |
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Colégio Brasileiro de Cirurgiões
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| Series: | Revista do Colégio Brasileiro de Cirurgiões |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912016000300149&lng=en&tlng=en |
| _version_ | 1818034795147427840 |
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| author | MARCELO GOMES GIRUNDI |
| author_facet | MARCELO GOMES GIRUNDI |
| author_sort | MARCELO GOMES GIRUNDI |
| collection | DOAJ |
| description | ABSTRACT Objective: to evaluate the effectiveness of Roux-en-Y gastric bypass in improving the glycemic profile of obese patients with type 2 Diabetes Mellitus (DM2) after 18 months of follow-up. Methods: four hundred sixty-eight pacients with DM2 and BMI ≥35 were submitted to Roux-en-Y gastric bypass, from 1998 to 2010. All patients were submitted to glycemic control analysis in the 3rd, 6th, 9th, 12th and 18th postoperative months. We considered: type 2 diabetic patients, the ones with fasting glucose ≥126mg/dl and HbA1C ≥6.5 in two dosages; high risk patients for diabetes, those who presented fasting glucose ≥ 100 to 125 mg/dl and HbA1C between 5.7%-6.4%; and normal patients, those presenting glucose <100mg/dl and HbA1C <5.7%. Such diagnostic criteria were based on the official position of Sociedade Brasileira de Diabetes, published in July, 2011. Results: The remission of DM2 was seen in 410 (87.6%) out of 468 patients 18 months after the surgery, that being a meaningful difference, with p<0.001. Fourty-eight (10.3%) patients sustained criteria for the disease and ten (2.1%) continued at high risk for DM2. Conclusions: Roux-en-Y gastric bypass was effective in the promotion and maintaince of long-term glycemic control. There are evidences showing that the remission of DM2 is not only related to weight loss and that other enteroinsular axis mechanisms must be involved. |
| first_indexed | 2024-12-10T06:44:50Z |
| format | Article |
| id | doaj.art-2ce84fac66184fd38ea7320a86f9065c |
| institution | Directory Open Access Journal |
| issn | 1809-4546 |
| language | English |
| last_indexed | 2024-12-10T06:44:50Z |
| publisher | Colégio Brasileiro de Cirurgiões |
| record_format | Article |
| series | Revista do Colégio Brasileiro de Cirurgiões |
| spelling | doaj.art-2ce84fac66184fd38ea7320a86f9065c2022-12-22T01:58:40ZengColégio Brasileiro de CirurgiõesRevista do Colégio Brasileiro de Cirurgiões1809-454643314915310.1590/0100-69912016003002S0100-69912016000300149Type 2 Diabetes Mellitus remission eighteen months after Roux-en-Y gastric bypass.MARCELO GOMES GIRUNDIABSTRACT Objective: to evaluate the effectiveness of Roux-en-Y gastric bypass in improving the glycemic profile of obese patients with type 2 Diabetes Mellitus (DM2) after 18 months of follow-up. Methods: four hundred sixty-eight pacients with DM2 and BMI ≥35 were submitted to Roux-en-Y gastric bypass, from 1998 to 2010. All patients were submitted to glycemic control analysis in the 3rd, 6th, 9th, 12th and 18th postoperative months. We considered: type 2 diabetic patients, the ones with fasting glucose ≥126mg/dl and HbA1C ≥6.5 in two dosages; high risk patients for diabetes, those who presented fasting glucose ≥ 100 to 125 mg/dl and HbA1C between 5.7%-6.4%; and normal patients, those presenting glucose <100mg/dl and HbA1C <5.7%. Such diagnostic criteria were based on the official position of Sociedade Brasileira de Diabetes, published in July, 2011. Results: The remission of DM2 was seen in 410 (87.6%) out of 468 patients 18 months after the surgery, that being a meaningful difference, with p<0.001. Fourty-eight (10.3%) patients sustained criteria for the disease and ten (2.1%) continued at high risk for DM2. Conclusions: Roux-en-Y gastric bypass was effective in the promotion and maintaince of long-term glycemic control. There are evidences showing that the remission of DM2 is not only related to weight loss and that other enteroinsular axis mechanisms must be involved.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912016000300149&lng=en&tlng=enBariatric Surgery. Diabetes MellitusType 2. Gastric Bypass. Obesity. Gastroplasty. |
| spellingShingle | MARCELO GOMES GIRUNDI Type 2 Diabetes Mellitus remission eighteen months after Roux-en-Y gastric bypass. Revista do Colégio Brasileiro de Cirurgiões Bariatric Surgery. Diabetes Mellitus Type 2. Gastric Bypass. Obesity. Gastroplasty. |
| title | Type 2 Diabetes Mellitus remission eighteen months after Roux-en-Y gastric bypass. |
| title_full | Type 2 Diabetes Mellitus remission eighteen months after Roux-en-Y gastric bypass. |
| title_fullStr | Type 2 Diabetes Mellitus remission eighteen months after Roux-en-Y gastric bypass. |
| title_full_unstemmed | Type 2 Diabetes Mellitus remission eighteen months after Roux-en-Y gastric bypass. |
| title_short | Type 2 Diabetes Mellitus remission eighteen months after Roux-en-Y gastric bypass. |
| title_sort | type 2 diabetes mellitus remission eighteen months after roux en y gastric bypass |
| topic | Bariatric Surgery. Diabetes Mellitus Type 2. Gastric Bypass. Obesity. Gastroplasty. |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912016000300149&lng=en&tlng=en |
| work_keys_str_mv | AT marcelogomesgirundi type2diabetesmellitusremissioneighteenmonthsafterrouxenygastricbypass |