Genotoxic, Cytotoxic, Antigenotoxic, and Anticytotoxic Effects of Sulfonamide Chalcone Using the Ames Test and the Mouse Bone Marrow Micronucleus Test.

Chalcones present several biological activities and sulfonamide chalcone derivatives have shown important biological applications, including antitumor activity. In this study, genotoxic, cytotoxic, antigenotoxic, and anticytotoxic activities of the sulfonamide chalcone N-{4-[3-(4-nitrophenyl)prop-2-...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Carolina Ribeiro E Silva, Flávio Fernandes Veloso Borges, Aline Bernardes, Caridad Noda Perez, Daniela de Melo E Silva, Lee Chen-Chen
Format: Artikel
Sprache:English
Veröffentlicht: Public Library of Science (PLoS) 2015-01-01
Schriftenreihe:PLoS ONE
Online Zugang:http://europepmc.org/articles/PMC4559391?pdf=render