State of Cell Unjamming Correlates with Distant Metastasis in Cancer Patients
Pathological morphological changes in tumor tissue enable collective cancer cell unjamming, a cellular motility transition. However, fundamental questions remain: Is unjamming essential for tumor progression? Which different unjamming states can be found in patients? Here, vital cell tracking in pat...
Main Authors: | Pablo Gottheil, Jürgen Lippoldt, Steffen Grosser, Frédéric Renner, Mohamad Saibah, Dimitrij Tschodu, Anne-Kathrin Poßögel, Anne-Sophie Wegscheider, Bernhard Ulm, Kay Friedrichs, Christoph Lindner, Christoph Engel, Markus Löffler, Benjamin Wolf, Michael Höckel, Bahriye Aktas, Hans Kubitschke, Axel Niendorf, Josef A. Käs |
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Format: | Article |
Language: | English |
Published: |
American Physical Society
2023-07-01
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Series: | Physical Review X |
Online Access: | http://doi.org/10.1103/PhysRevX.13.031003 |
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