Comprehensive Insight into Colorectal Cancer Metabolites and Lipids for Human Serum: A Proof-of-Concept Study

Comprehensive Insight into Colorectal Cancer Metabolites and Lipids for Human Serum: A Proof-of-Concept Study

Colorectal cancer (CRC) ranks as the third most frequently diagnosed cancer and the second leading cause of cancer-related deaths. The current endoscopic-based or stool-based diagnostic techniques are either highly invasive or lack sufficient sensitivity. Thus, there is a need for less invasive and...

Full description

Bibliographic Details
Main Authors:	Kinjal Bhatt, Titziana Orlando, Marie-Alice Meuwis, Edouard Louis, Pierre-Hugues Stefanuto, Jean-François Focant
Format:	Article
Language:	English
Published:	MDPI AG 2023-06-01
Series:	International Journal of Molecular Sciences
Subjects:	colorectal cancer metabolomics lipidomics blood serum chemometrics
Online Access:	https://www.mdpi.com/1422-0067/24/11/9614

Similar Items

Lipid Serum Profiling of Boar-Tainted and Untainted Pigs Using GC×GC–TOFMS: An Exploratory Study
by: Kinjal Bhatt, et al.
Published: (2022-11-01)

The Application of Chemometrics in Metabolomic and Lipidomic Analysis Data Presentation for Halal Authentication of Meat Products
by: Vevi Maritha, et al.
Published: (2022-11-01)

Metabolomic and Lipidomic Analysis of the Colorectal Adenocarcinoma Cell Line HT29 in Hypoxia and Reoxygenation
by: Juan Carlos Alarcon Barrera, et al.
Published: (2023-07-01)

Comparative sphingolipidomics of disease-causing trypanosomatids reveal unique lifecycle- and taxonomy-specific lipid chemistries
by: Guan, Xue Li, et al.
Published: (2017)

Metabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS
by: Sylvia K. Neef, et al.
Published: (2020-12-01)

Short-Term Stability of Serum and Liver Extracts for Untargeted Metabolomics and Lipidomics
by: Jiri Hricko, et al.
Published: (2023-04-01)

Phenotypic and Metabolomic Characterization of 3D Lung Cell Cultures Exposed to Airborne Particulate Matter from Three Air Quality Network Stations in Catalonia
by: Paula Villasclaras, et al.
Published: (2022-10-01)

Human Milk Lipids and Small Metabolites: Maternal and Microbial Origins
by: Lisa F. Stinson, et al.
Published: (2023-03-01)

Effects of perinatal stress on the metabolites and lipids in plasma of dairy goats
by: Yan Huang, et al.
Published: (2023-05-01)

Serum untargeted lipidomics by UHPLC-ESI-HRMS aids the biomarker discovery of colorectal adenoma
by: Hailin Zhou, et al.
Published: (2022-03-01)

NMR Metabolomics in Serum Fingerprinting of Schizophrenia Patients in a Serbian Cohort
by: Katarina Simić, et al.
Published: (2022-07-01)

Blood-Derived Lipid and Metabolite Biomarkers in Cardiovascular Research from Clinical Studies: A Recent Update
by: Dipali Kale, et al.
Published: (2023-12-01)

Serum Metabolomic and Lipidomic Profiling Reveals Novel Biomarkers of Efficacy for Benfotiamine in Alzheimer’s Disease
by: Ruchika Bhawal, et al.
Published: (2021-12-01)

Novel insights into the mechanisms of hard exudate in diabetic retinopathy: Findings of serum lipidomic and metabolomics profiling
by: Yinchen Shen, et al.
Published: (2023-04-01)

Bioinformatics Supported Liquid Chromatography–Mass Spectrometry for Characterization of Bacterial Metabolites
by: Elwira Sieniawska
Published: (2022-04-01)

Lipid Metabolite Biomarkers in Cardiovascular Disease: Discovery and Biomechanism Translation from Human Studies
by: Peter McGranaghan, et al.
Published: (2021-09-01)

Identification of Metabolite and Lipid Profiles in a Segregating Peach Population Associated with Mealiness in <i>Prunus persica</i> (L.) Batsch
by: Victoria Lillo-Carmona, et al.
Published: (2020-04-01)

Metabolomic Profiling of Bipolar Disorder by <sup>1</sup>H-NMR in Serbian Patients
by: Katarina Simić, et al.
Published: (2023-04-01)

CHANGES OF LIPIDOM IN COLORECTAL CANCER
by: M. V. Kruchinina, et al.
Published: (2018-03-01)

Multiplatform Metabolomics Characterization Reveals Novel Metabolites and Phospholipid Compositional Rules of <i>Haemophilus influenzae</i> Rd KW20
by: Miguel Fernández-García, et al.
Published: (2023-07-01)

Linking Gut Microbiome and Lipid Metabolism: Moving beyond Associations
by: Santosh Lamichhane, et al.
Published: (2021-01-01)

Effectiveness of mid-infrared spectroscopy for the prediction of cow milk metabolites
by: M. Franzoi, et al.
Published: (2023-08-01)

Feeding of fish oil and medium-chain triglycerides to canines impacts circulating structural and energetic lipids, endocannabinoids, and non-lipid metabolite profiles
by: Matthew I. Jackson, et al.
Published: (2023-08-01)

Lipid Profiling of Alzheimer’s Disease Brain Highlights Enrichment in Glycerol(phospho)lipid, and Sphingolipid Metabolism
by: Sumeyya Akyol, et al.
Published: (2021-09-01)

Growth Substrate and Prophage Induction Collectively Influence Metabolite and Lipid Profiles in a Marine Bacterium
by: Jonelle T. R. Basso, et al.
Published: (2022-10-01)

KRAS, A Prime Mediator in Pancreatic Lipid Synthesis through Extra Mitochondrial Glutamine and Citrate Metabolism
by: Isaac James Muyinda, et al.
Published: (2021-05-01)

Lipid Profiles of Human Serum Fractions Enhanced with CD9 Antibody-Immobilized Magnetic Beads
by: Suzumi M. Tokuoka, et al.
Published: (2022-03-01)

Revolutionizing Blood Collection: Innovations, Applications, and the Potential of Microsampling Technologies for Monitoring Metabolites and Lipids
by: Eleonora Bossi, et al.
Published: (2024-01-01)

Circulating metabolites and molecular lipid species are associated with future cardiovascular morbidity and mortality in type 1 diabetes
by: Luis F. Ferreira-Divino, et al.
Published: (2022-07-01)

N-arachidonylglycine is a caloric state-dependent circulating metabolite which regulates human CD4+T cell responsiveness
by: Allison M. Meadows, et al.
Published: (2023-05-01)

Multi-Omics Analysis to Visualize Ecotype-Specific Heterogeneity of the Metabolites in the Mesocarp Tissue of Three Avocado (<i>Persea Americana</i> Mill.) Ecotypes
by: Yu Ge, et al.
Published: (2021-05-01)

Untargeted Multiomics Approach Coupling Lipidomics and Metabolomics Profiling Reveals New Insights in Diabetic Retinopathy
by: Patricia Ancel, et al.
Published: (2023-07-01)

An Optimized Dual Extraction Method for the Simultaneous and Accurate Analysis of Polar Metabolites and Lipids Carried out on Single Biological Samples
by: Joran Villaret-Cazadamont, et al.
Published: (2020-08-01)

Integrated metabolomics and lipidomics analyses suggest the temperature-dependent lipid desaturation promotes aflatoxin biosynthesis in Aspergillus flavus
by: Shaowen Wu, et al.
Published: (2023-03-01)

Disordered Gut Microbiota in Colorectal Tumor-Bearing Mice Altered Serum Metabolome Related to Fufangchangtai
by: Mengmeng Cai, et al.
Published: (2022-05-01)

Comparative Metabolite Fingerprinting of Four Different Cinnamon Species Analyzed via UPLC–MS and GC–MS and Chemometric Tools
by: Mohamed A. Farag, et al.
Published: (2022-05-01)

Distinct changes in serum metabolites and lipid species in the onset and progression of NAFLD in Obese Chinese
by: Jiarui Chen, et al.
Published: (2024-12-01)

Characterization of Brazilian floral honey produced in the states of Santa Catarina and São Paulo using quantitative nuclear magnetic resonance (qNMR) spectroscopy
by: Aline Nunes, et al.
Published: (2023-12-01)

Application of ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS) metabolomic fingerprinting to characterise GM and conventional maize varieties
by: Lukáš VÁCLAVÍK, et al.
Published: (2013-08-01)

Pre-analytical sample handling standardization for reliable measurement of metabolites and lipids in LC-MS-based clinical research
by: A. Sens, et al.
Published: (2023-04-01)