Elucidating the mechanisms of formononetin in modulating atherosclerotic plaque formation in ApoE-/- mice

Elucidating the mechanisms of formononetin in modulating atherosclerotic plaque formation in ApoE-/- mice

Abstract Background Atherosclerosis(AS) poses a pressing challenge in contemporary medicine. Formononetin (FMN) plays a crucial role in its prevention and treatment. However, the detailed impact of FMN on the stability of atherosclerotic plaques and its underlying mechanisms remain to be elucidated....

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Bibliographic Details
Main Authors: Ying He, Youde Cai, Dingling Wei, Liping Cao, Qiansong He, Yazhou Zhang
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Cardiovascular Disorders
Subjects:
Formononetin
α7nAChR
Atherosclerosis
JAK/STAT
Macrophages
Online Access:https://doi.org/10.1186/s12872-024-03774-6

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