Evaluation of the potential of Mycobacterium smegmatis as vaccine Candidate against tuberculosis by in silico and in vivo studies

Evaluation of the potential of Mycobacterium smegmatis as vaccine Candidate against tuberculosis by in silico and in vivo studies

In this study, we scanned multiple published databases of gene expression in vivo of M. tuberculosis at different phases of infection in animals and humans, to select 38 proteins that are highly expressed in the active, latent and reactivation phases. The selected proteins were predicted for T and B...

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Bibliographic Details
Main Authors: Le Thuy Nguyen Thi, Reinier Borrero Maura, Sonsire Férnandez, Giselle Reyes, José Luis Perez, Fátima Reyes, María de los Angeles García, Midrey Fariñas, Juan Francisco Infante, Yanely Tirado, Alina Puig, Gustavo Sierra, Nadine Álvarez, Juan Carlos Ramírez, María Elena Sarmiento, Mohd-Nor Norazmi, Armando Acosta
Format: Article
Language:English
Published: Finlay Ediciones 2010-04-01
Series:VacciMonitor
Subjects:
Mycobacterium tuberculosis
Mycobacterium smegmatis
epitopes
prediction
Online Access:http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1025-028X2010000100004&lng=es&nrm=iso

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