Activity of Meropenem and Ciprofloxacin in vitro Against Oxacillin Resistant Staphylococcus aureus
A total of 150 clinical specimens were collected from patients attending Medical city Hospital in Baghdad to isolation and identification Staphylococcus aureus on species level by Api staph 20 system (Biomereux , france). 33 (22%) isolates were isolated from Staphylococcus aureus, this isolates div...
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| Format: | Article |
| Language: | English |
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College of Pharmacy / Mustansiriyah University
2010-12-01
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| Series: | Al-Mustansiriyah Journal of Pharmaceutical Sciences |
| Online Access: | https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/339 |
| _version_ | 1797223844894736384 |
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| author | Suhad Faisal Hatem Al-Mugdadi |
| author_facet | Suhad Faisal Hatem Al-Mugdadi |
| author_sort | Suhad Faisal Hatem Al-Mugdadi |
| collection | DOAJ |
| description |
A total of 150 clinical specimens were collected from patients attending Medical city Hospital in Baghdad to isolation and identification Staphylococcus aureus on species level by Api staph 20 system (Biomereux , france). 33 (22%) isolates were isolated from Staphylococcus aureus, this isolates divided according to source of isolate: 15 (37.5%) isolate from wounds, 10 (20%) isolate from bone infection, 7 (50%) isolate from nasal and throat swabs, one (2%) isolate from urine.
Thirteen antibiotics were used for sensitivity test; all isolate were resistance to Pencillin (100%), Ampicillin (100%), and while Erythromycin (75.8%). Among the various antimicrobial Oxacillin showed high resisance (69.6%), most effective antibiotics on S. aureus were Vancomycin (100%), Meropenem (100%), while Amikacin and Ciprofloxacin in Percentage 79%, 76% recpectively.
In vitro minimum inhibitory concentration (MIC) of Meropenem and Ciprofloxacin were done to determined inhibition effect against all isolates of S.
aureus Which is resist to Oxacillin( 23 isolate ) in Serial concentration (4-1024) μg / ml, S. aureus was resistant to Meropenem in percentage 70% in break point
≥ 16, while Ciprofloxacim was resistant in percentage 74% in berak point ≥4.
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| first_indexed | 2024-04-24T13:43:41Z |
| format | Article |
| id | doaj.art-2cf917d8a85f456da52c1eddfe131f3e |
| institution | Directory Open Access Journal |
| issn | 1815-0993 2959-183X |
| language | English |
| last_indexed | 2024-04-24T13:43:41Z |
| publishDate | 2010-12-01 |
| publisher | College of Pharmacy / Mustansiriyah University |
| record_format | Article |
| series | Al-Mustansiriyah Journal of Pharmaceutical Sciences |
| spelling | doaj.art-2cf917d8a85f456da52c1eddfe131f3e2024-04-04T06:59:06ZengCollege of Pharmacy / Mustansiriyah UniversityAl-Mustansiriyah Journal of Pharmaceutical Sciences1815-09932959-183X2010-12-018210.32947/ajps.v8i2.339Activity of Meropenem and Ciprofloxacin in vitro Against Oxacillin Resistant Staphylococcus aureusSuhad Faisal Hatem Al-Mugdadi0Dept. of Medical Microbiology& Biotechnology, College of Pharmacy, University of Al-Mustansiriya. A total of 150 clinical specimens were collected from patients attending Medical city Hospital in Baghdad to isolation and identification Staphylococcus aureus on species level by Api staph 20 system (Biomereux , france). 33 (22%) isolates were isolated from Staphylococcus aureus, this isolates divided according to source of isolate: 15 (37.5%) isolate from wounds, 10 (20%) isolate from bone infection, 7 (50%) isolate from nasal and throat swabs, one (2%) isolate from urine. Thirteen antibiotics were used for sensitivity test; all isolate were resistance to Pencillin (100%), Ampicillin (100%), and while Erythromycin (75.8%). Among the various antimicrobial Oxacillin showed high resisance (69.6%), most effective antibiotics on S. aureus were Vancomycin (100%), Meropenem (100%), while Amikacin and Ciprofloxacin in Percentage 79%, 76% recpectively. In vitro minimum inhibitory concentration (MIC) of Meropenem and Ciprofloxacin were done to determined inhibition effect against all isolates of S. aureus Which is resist to Oxacillin( 23 isolate ) in Serial concentration (4-1024) μg / ml, S. aureus was resistant to Meropenem in percentage 70% in break point ≥ 16, while Ciprofloxacim was resistant in percentage 74% in berak point ≥4. https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/339 |
| spellingShingle | Suhad Faisal Hatem Al-Mugdadi Activity of Meropenem and Ciprofloxacin in vitro Against Oxacillin Resistant Staphylococcus aureus Al-Mustansiriyah Journal of Pharmaceutical Sciences |
| title | Activity of Meropenem and Ciprofloxacin in vitro Against Oxacillin Resistant Staphylococcus aureus |
| title_full | Activity of Meropenem and Ciprofloxacin in vitro Against Oxacillin Resistant Staphylococcus aureus |
| title_fullStr | Activity of Meropenem and Ciprofloxacin in vitro Against Oxacillin Resistant Staphylococcus aureus |
| title_full_unstemmed | Activity of Meropenem and Ciprofloxacin in vitro Against Oxacillin Resistant Staphylococcus aureus |
| title_short | Activity of Meropenem and Ciprofloxacin in vitro Against Oxacillin Resistant Staphylococcus aureus |
| title_sort | activity of meropenem and ciprofloxacin in vitro against oxacillin resistant staphylococcus aureus |
| url | https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/339 |
| work_keys_str_mv | AT suhadfaisalhatemalmugdadi activityofmeropenemandciprofloxacininvitroagainstoxacillinresistantstaphylococcusaureus |