<i>HSD3B1</i> Expression Is Upregulated by Interleukin 4 in HT-29 Colon Cancer Cells via Multiple Signaling Pathways

<i>HSD3B1</i> Expression Is Upregulated by Interleukin 4 in HT-29 Colon Cancer Cells via Multiple Signaling Pathways

3β-Hydroxysteroid dehydrogenase/isomerase is essential for the synthesis of active steroid hormones. Interleukin 4 (IL4) induces the expression of <i>HSD3B1</i> in various human cancer cell lines. Here, we demonstrated that administration of IL4 to an HT-29 colon cancer cell line induced...

Full description

Bibliographic Details
Main Authors: Hsin-Mei Chen, Pei-Yu Hung, Chih-Hung Chen, Yu-Jhen Yu, Ming-Shan Syu, Meng-Chun Hu
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
HSD3B1
IL4
steroidogenesis
colon cancer
Online Access:https://www.mdpi.com/1422-0067/23/21/13572

Similar Items

Similar Items