Inhaled silica nanoparticles exacerbate atherosclerosis through skewing macrophage polarization towards M1 phenotype

Inhaled silica nanoparticles exacerbate atherosclerosis through skewing macrophage polarization towards M1 phenotype

Background and aims: Exposure to environmental nanoparticles is related to the adverse impact on health, including cardiovascular system. Various forms of nanoparticles have been reported to interact with endothelium and induce inflammation. However, the potential role of nanoparticles in the pathog...

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Bibliographic Details
Main Authors: Kamila Stachyra, Anna Wiśniewska, Anna Kiepura, Katarzyna Kuś, Filip Rolski, Klaudia Czepiel, Łukasz Chmura, Grzegorz Majka, Marcin Surmiak, Justyna Polaczek, Rudi van Eldik, Maciej Suski, Rafał Olszanecki
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Atherosclerosis
Nanoparticles
Atherosclerotic plaque
ApoE-knockout mice
Macrophages
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651321012240

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