Intraparenchymal NGF Infusions Rescue Degenerating Cholinergic Neurons
Nerve growth factor (NGF) exerts both trophic (cell survival) and tropic (axonal growth-promoting) effects on several neuronal populations. In particular, its robust ability to prevent lesion-induced and spontaneous age-related basal forebrain cholinergic neuronal degeneration, and to promote mnemon...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2000-09-01
|
| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.1177/096368970000900508 |