Resistance to cisplatin does not affect sensitivity of human ovarian cancer cell lines to mifepristone cytotoxicity

Resistance to cisplatin does not affect sensitivity of human ovarian cancer cell lines to mifepristone cytotoxicity

<p>Abstract</p> <p>Background</p> <p>The prototypical antiprogestin mifepristone exhibits potent growth inhibition activity towards ovarian cancer cells <it>in vitro </it>and <it>in vivo</it>. The aim of this research was to establish whether mif...

Full description

Bibliographic Details
Main Authors:	Seidel Erin E, Goyeneche Alicia A, Freeburg Elizabeth M, Telleria Carlos M
Format:	Article
Language:	English
Published:	BMC 2009-02-01
Series:	Cancer Cell International
Online Access:	http://www.cancerci.com/content/9/1/4

Similar Items

Mifepristone prevents repopulation of ovarian cancer cells escaping cisplatin-paclitaxel therapy
by: Gamarra-Luques Carlos D, et al.
Published: (2012-06-01)

Mifepristone inhibits non-small cell lung carcinoma cellular escape from DNA damaging cisplatin
by: Heather E. Kapperman, et al.
Published: (2018-11-01)

The metastatic capacity of high-grade serous ovarian cancer cells changes along disease progression: inhibition by mifepristone
by: Sabrina J. Ritch, et al.
Published: (2022-12-01)

Anticancer effects of mifepristone on human uveal melanoma cells
by: Prisca Bustamante Alvarez, et al.
Published: (2021-11-01)

Advanced assessment of migration and invasion of cancer cells in response to mifepristone therapy using double fluorescence cytochemical labeling
by: Sabrina J. Ritch, et al.
Published: (2019-04-01)

Antiprogestin mifepristone inhibits the growth of cancer cells of reproductive and non-reproductive origin regardless of progesterone receptor expression
by: Ortbahn Casey T, et al.
Published: (2011-05-01)

Cytostasis and morphological changes induced by mifepristone in human metastatic cancer cells involve cytoskeletal filamentous actin reorganization and impairment of cell adhesion dynamics
by: Brandhagen BreeAnn N, et al.
Published: (2013-01-01)

Mifepristone increases mRNA translation rate, triggers the unfolded protein response, increases autophagic flux, and kills ovarian cancer cells in combination with proteasome or lysosome inhibitors
by: Lei Zhang, et al.
Published: (2016-08-01)

Pharmacokinetics and Anti-Tumor Efficacy of PEGylated Liposomes Co-Loaded with Cisplatin and Mifepristone
by: Karen Ocaña-Arakachi, et al.
Published: (2023-09-01)

Liposomes Co-Encapsulating Cisplatin/Mifepristone Improve the Effect on Cervical Cancer: In Vitro and In Vivo Assessment
by: Fabricio Ledezma-Gallegos, et al.
Published: (2020-09-01)

Management of early pregnancy loss by reproductive endocrinologists: does access to mifepristone matter?
by: Zachary S. Anderson, M.D., et al.
Published: (2024-09-01)

Antitumor effect of mifepristone on human endometrial stromal cell line
by: Luković Jovan, et al.
Published: (2021-01-01)

Distinct clinicopathological features of ovarian endometriosis after long-term exposure to mifepristone
by: Yongmiao Pan, et al.
Published: (2022-11-01)

Histomorphometric analysis of goat uterine tissue on in vitro exposure with ovarian hormones and mifepristone
by: R. K. Sharma, et al.
Published: (2021-03-01)

Mifepristone-Induced Hypothyroidism
by: Niketa Kalara MD, et al.
Published: (2023-08-01)

Vitality, viability, long-term clonogenic survival, cytotoxicity, cytostasis and lethality: what do they mean when testing new investigational oncology drugs?
by: Benjamin N. Forgie, et al.
Published: (2024-01-01)

The timing of caffeic acid treatment with cisplatin determines sensitization or resistance of ovarian carcinoma cell lines
by: R. Sirota, et al.
Published: (2017-04-01)

Molecular mechanisms underlying mifepristone's agonistic action on ovarian cancer progressionResearch in context
by: Donata Ponikwicka-Tyszko, et al.
Published: (2019-09-01)

Metformin Suppresses Ovarian Cancer Growth and Metastasis with Enhancement of Cisplatin Cytotoxicity In Vivo
by: Ramandeep Rattan, et al.
Published: (2011-05-01)

Mifepristone and Misoprostol for early Abortion
by: Achala Vaidya
Published: (2006-01-01)

Nutlin-3 sensitizes nasopharyngeal carcinoma cells to cisplatin-induced cytotoxicity
by: Voon, Y.L., et al.
Published: (2015)

NMR Metabolomics of Primary Ovarian Cancer Cells in Comparison to Established Cisplatin-Resistant and -Sensitive Cell Lines
by: Veronica Ghini, et al.
Published: (2024-04-01)

Nuclear COMMD1 Is Associated with Cisplatin Sensitivity in Ovarian Cancer.
by: Alina Fedoseienko, et al.
Published: (2016-01-01)

Progesterone-Calcitriol Combination Enhanced Cytotoxicity of Cisplatin in Ovarian and Endometrial Cancer Cells In Vitro
by: Ana Paucarmayta, et al.
Published: (2020-03-01)

Low-dose LBH589 increases the sensitivity of cisplatin to cisplatin-resistant ovarian cancer cells
by: Yen-Ying Ma, et al.
Published: (2011-06-01)

Enhancement of Cisplatin Sensitivity by Microwave Radiation in Ovarian Cancer Cells
by: Mansour Tayebi-khorami, et al.
Published: (2022-04-01)

Exogenous estradiol enhances apoptosis in regressing post-partum rat corpora lutea possibly mediated by prolactin
by: Telleria Carlos M, et al.
Published: (2005-08-01)

RuX: A Novel, Flexible, and Sensitive Mifepristone-Induced Transcriptional Regulation System
by: Anne Meinzinger, et al.
Published: (2023-01-01)

Use of mifepristone in preparation of uterine cervix for delivery
by: V. A. Petrukhin, et al.
Published: (2013-12-01)

Mifepristone increases the cytotoxicity of uterine natural killer cells by acting as a glucocorticoid antagonist via ERK activation.
by: Yuezhou Chen, et al.
Published: (2012-01-01)

Nanotechnology-Based Cisplatin Intracellular Delivery to Enhance Chemo-Sensitivity of Ovarian Cancer
by: Bortot B, et al.
Published: (2020-07-01)

The inhibitory effect of doxycycline on cisplatin-sensitive and -resistant epithelial ovarian cancer.
by: Wei Wu, et al.
Published: (2014-01-01)

Silencing of NLRP3 Sensitizes Chemoresistant Ovarian Cancer Cells to Cisplatin
by: Weijia Li, et al.
Published: (2023-01-01)

Investigating the Effects of Morphine on Survival and Sensitivity to Cisplatin in Ovarian Cancer Cells
by: Maryam Rezaeigazik, et al.
Published: (2019-09-01)

FOLR1 increases sensitivity to cisplatin treatment in ovarian cancer cells
by: Ming-ju Huang, et al.
Published: (2018-02-01)

The effect of PAFR on cisplatin sensitivity in ovarian cancer cells and its mechanism
by: YU Yi, CONG Qing, XU Congjian, JIANG Wei
Published: (2021-11-01)

First-line chemotherapy for advanced ovarian cancer: paclitaxel, cisplatin and the evidence
by: Sandercock, J, et al.
Published: (1998)

Cytotoxicity of natural and synthetic cannabinoids and their synergistic antiproliferative effects with cisplatin in human ovarian cancer cells
by: Ying Chen, et al.
Published: (2024-11-01)

A COMPARATIVE STUDY BETWEEN MIFEPRISTONE VS. PLACEBO AS AN UTERINE SENSITIZER FOR SECOND TRIMESTER ABORTIONS
by: Meetali Parashar, et al.
Published: (2019-12-01)

Mifepristone Repurposing in Treatment of High-Grade Gliomas
by: Monserrat Llaguno-Munive, et al.
Published: (2021-02-01)