Pichinde Virus Infection of Outbred Hartley Guinea Pigs as a Surrogate Animal Model for Human Lassa Fever: Histopathological and Immunohistochemical Analyses

Pichinde Virus Infection of Outbred Hartley Guinea Pigs as a Surrogate Animal Model for Human Lassa Fever: Histopathological and Immunohistochemical Analyses

Lassa virus (LASV) is a mammarenavirus (arenavirus) that causes zoonotic infection in humans that can lead to fatal hemorrhagic Lassa fever (LF) disease. Currently, there are no FDA-approved vaccines or therapeutics against LASV. Development of treatments against LF and other related arenavirus-indu...

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Bibliographic Details
Main Authors: Wun-Ju Shieh, Shuiyun Lan, Sherif R. Zaki, Hinh Ly, Yuying Liang
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Pathogens
Subjects:
mammarenavirus
arenavirus
Pichinde virus
Lassa virus
animal model
pathology
Online Access:https://www.mdpi.com/2076-0817/9/7/579

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