Impaired bidirectional communication between interneurons and oligodendrocyte precursor cells affects social cognitive behavior
Early postnatal interruption of the bidirectional GABA/TNFSF12 signaling between parvalbumin-positive interneurons and oligodendrocyte precursor cells impairs correct prefrontal cortical network activity and social cognitive behavior later in life.
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-29020-1 |
| _version_ | 1818315594782474240 |
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| author | Li-Pao Fang Na Zhao Laura C. Caudal Hsin-Fang Chang Renping Zhao Ching-Hsin Lin Nadine Hainz Carola Meier Bernhard Bettler Wenhui Huang Anja Scheller Frank Kirchhoff Xianshu Bai |
| author_facet | Li-Pao Fang Na Zhao Laura C. Caudal Hsin-Fang Chang Renping Zhao Ching-Hsin Lin Nadine Hainz Carola Meier Bernhard Bettler Wenhui Huang Anja Scheller Frank Kirchhoff Xianshu Bai |
| author_sort | Li-Pao Fang |
| collection | DOAJ |
| description | Early postnatal interruption of the bidirectional GABA/TNFSF12 signaling between parvalbumin-positive interneurons and oligodendrocyte precursor cells impairs correct prefrontal cortical network activity and social cognitive behavior later in life. |
| first_indexed | 2024-12-13T09:08:01Z |
| format | Article |
| id | doaj.art-2d0a09c506374f3cb705f43e9434264f |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-13T09:08:01Z |
| publishDate | 2022-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-2d0a09c506374f3cb705f43e9434264f2022-12-21T23:53:02ZengNature PortfolioNature Communications2041-17232022-03-0113111410.1038/s41467-022-29020-1Impaired bidirectional communication between interneurons and oligodendrocyte precursor cells affects social cognitive behaviorLi-Pao Fang0Na Zhao1Laura C. Caudal2Hsin-Fang Chang3Renping Zhao4Ching-Hsin Lin5Nadine Hainz6Carola Meier7Bernhard Bettler8Wenhui Huang9Anja Scheller10Frank Kirchhoff11Xianshu Bai12Molecular Physiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), University of SaarlandMolecular Physiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), University of SaarlandMolecular Physiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), University of SaarlandCellular Neurophysiology, CIPMM, University of SaarlandBiophysics, CIPMM, University of SaarlandCellular Neurophysiology, CIPMM, University of SaarlandDepartment of Anatomy and Cell Biology, University of SaarlandDepartment of Anatomy and Cell Biology, University of SaarlandDepartment of Biomedicine, University of BaselMolecular Physiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), University of SaarlandMolecular Physiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), University of SaarlandMolecular Physiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), University of SaarlandMolecular Physiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), University of SaarlandEarly postnatal interruption of the bidirectional GABA/TNFSF12 signaling between parvalbumin-positive interneurons and oligodendrocyte precursor cells impairs correct prefrontal cortical network activity and social cognitive behavior later in life.https://doi.org/10.1038/s41467-022-29020-1 |
| spellingShingle | Li-Pao Fang Na Zhao Laura C. Caudal Hsin-Fang Chang Renping Zhao Ching-Hsin Lin Nadine Hainz Carola Meier Bernhard Bettler Wenhui Huang Anja Scheller Frank Kirchhoff Xianshu Bai Impaired bidirectional communication between interneurons and oligodendrocyte precursor cells affects social cognitive behavior Nature Communications |
| title | Impaired bidirectional communication between interneurons and oligodendrocyte precursor cells affects social cognitive behavior |
| title_full | Impaired bidirectional communication between interneurons and oligodendrocyte precursor cells affects social cognitive behavior |
| title_fullStr | Impaired bidirectional communication between interneurons and oligodendrocyte precursor cells affects social cognitive behavior |
| title_full_unstemmed | Impaired bidirectional communication between interneurons and oligodendrocyte precursor cells affects social cognitive behavior |
| title_short | Impaired bidirectional communication between interneurons and oligodendrocyte precursor cells affects social cognitive behavior |
| title_sort | impaired bidirectional communication between interneurons and oligodendrocyte precursor cells affects social cognitive behavior |
| url | https://doi.org/10.1038/s41467-022-29020-1 |
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