Once weekly paclitaxel associated with a fixed dose of oral metronomic cyclophosphamide: a dose-finding phase 1 trial

Once weekly paclitaxel associated with a fixed dose of oral metronomic cyclophosphamide: a dose-finding phase 1 trial

Abstract Background The primary aim of this trial was to determine the recommended phase II dose (RP2D) of weekly paclitaxel (wP) administered in combination with oral metronomic cyclophosphamide (OMC). Methods Patients ≥ 18 years of age with refractory metastatic cancers were eligible if no standar...

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Bibliographic Details
Main Authors: Diane Pannier, Antoine Adenis, Emilie Bogart, Eric Dansin, Stéphanie Clisant-Delaine, Emilie Decoupigny, Anne Lesoin, Eric Amela, Sandrine Ducornet, Jean-Pierre Meurant, Marie-Cécile Le Deley, Nicolas Penel
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Cancer
Subjects:
Dose-finding phase 1 trial
Metronomic cyclophosphamide
Weekly paclitaxel
Online Access:http://link.springer.com/article/10.1186/s12885-018-4678-x

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