Wuchereria bancrofti: Unusual Presentation as Pancytopenia

Wuchereria bancrofti is an endemic filarial nematode spread by a mosquito vector. The clinical manifestations vary from asymptomatic microfilaremeia to lymhoedema. We report two cases of microfilaria of Wuchereria bancrofti in bone marrow presenting as peripheral pancytopenia. The patient did not...

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Main Authors: Mili Jain, Ayush Shukla, Ashutosh Kumar, Rashmi Kushwaha, Uma Shankar Singh
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2016-07-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/8084/18960_CE(RA1)_F(T)_PF1(SWAK)_PFA(AK)_PF2(PAG).pdf
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author Mili Jain
Ayush Shukla
Ashutosh Kumar
Rashmi Kushwaha
Uma Shankar Singh
author_facet Mili Jain
Ayush Shukla
Ashutosh Kumar
Rashmi Kushwaha
Uma Shankar Singh
author_sort Mili Jain
collection DOAJ
description Wuchereria bancrofti is an endemic filarial nematode spread by a mosquito vector. The clinical manifestations vary from asymptomatic microfilaremeia to lymhoedema. We report two cases of microfilaria of Wuchereria bancrofti in bone marrow presenting as peripheral pancytopenia. The patient did not have any classical features of lymphoedema or elephantiasis. The diagnostic demonstration of microfilaria with unusual presentations has been done in cytology specimens from various sites. Microfilaria infection in association with peripheral blood pancytopenia has been rarely reported. An aetiopathological co-relation of these haematological manifestations of microfilaria needs further investigation.
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spelling doaj.art-2d0fca9c883c4716bd09d2f4947b33f42022-12-21T23:48:45ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-07-01107ED05ED0610.7860/JCDR/2016/18960.8084Wuchereria bancrofti: Unusual Presentation as PancytopeniaMili Jain0Ayush Shukla1Ashutosh Kumar2Rashmi Kushwaha3Uma Shankar Singh4Assistant Professor, Department of Pathology, King George’s Medical University, Lucknow, UP, India.Senior Resident, Department of Clinical Hematology, King George’s Medical University, Lucknow, UP, India.Professor, Department of Pathology, King George’s Medical University, Lucknow, UP, India.Associate Professor, Department of Pathology, King George’s Medical University, Lucknow, UP, India.Professor, Department of Pathology, King George’s Medical University, Lucknow, UP, India.Wuchereria bancrofti is an endemic filarial nematode spread by a mosquito vector. The clinical manifestations vary from asymptomatic microfilaremeia to lymhoedema. We report two cases of microfilaria of Wuchereria bancrofti in bone marrow presenting as peripheral pancytopenia. The patient did not have any classical features of lymphoedema or elephantiasis. The diagnostic demonstration of microfilaria with unusual presentations has been done in cytology specimens from various sites. Microfilaria infection in association with peripheral blood pancytopenia has been rarely reported. An aetiopathological co-relation of these haematological manifestations of microfilaria needs further investigation.https://jcdr.net/articles/PDF/8084/18960_CE(RA1)_F(T)_PF1(SWAK)_PFA(AK)_PF2(PAG).pdfbone marrow parasitematuration arrestmicrofilariae
spellingShingle Mili Jain
Ayush Shukla
Ashutosh Kumar
Rashmi Kushwaha
Uma Shankar Singh
Wuchereria bancrofti: Unusual Presentation as Pancytopenia
Journal of Clinical and Diagnostic Research
bone marrow parasite
maturation arrest
microfilariae
title Wuchereria bancrofti: Unusual Presentation as Pancytopenia
title_full Wuchereria bancrofti: Unusual Presentation as Pancytopenia
title_fullStr Wuchereria bancrofti: Unusual Presentation as Pancytopenia
title_full_unstemmed Wuchereria bancrofti: Unusual Presentation as Pancytopenia
title_short Wuchereria bancrofti: Unusual Presentation as Pancytopenia
title_sort wuchereria bancrofti unusual presentation as pancytopenia
topic bone marrow parasite
maturation arrest
microfilariae
url https://jcdr.net/articles/PDF/8084/18960_CE(RA1)_F(T)_PF1(SWAK)_PFA(AK)_PF2(PAG).pdf
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AT rashmikushwaha wuchereriabancroftiunusualpresentationaspancytopenia
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