Prolonged Response Induced by Single Agent Vemurafenib in a BRAF V600E Spinal Ganglioglioma: A Case Report and Review of the Literature

Prolonged Response Induced by Single Agent Vemurafenib in a BRAF V600E Spinal Ganglioglioma: A Case Report and Review of the Literature

Spinal ganglioglioma is a rare low-grade, slow-growing tumor of the central nervous system affecting mostly children and young adults. After surgery, some patients show tumor recurrence and/or malignant transformation. Gangliogliomas harbor molecular deficiencies such as mutations in the B-rapidly a...

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Bibliographic Details
Main Authors: Louis Garnier, François Ducray, Clotilde Verlut, Marcella-Ionela Mihai, Françoise Cattin, Antoine Petit, Elsa Curtit
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Oncology
Subjects:
central nervous system tumor
spinal cord
ganglioglioma
BRAF
vemurafenib
safety
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00177/full

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