P-glycoprotein efflux transporter: a key to pharmacokinetic modeling for methadone clearance in fetuses
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2023.1182571/full |
| _version_ | 1827954162601558016 |
|---|---|
| author | Harvey Ho En Zhang |
| author_facet | Harvey Ho En Zhang |
| author_sort | Harvey Ho |
| collection | DOAJ |
| first_indexed | 2024-04-09T14:25:52Z |
| format | Article |
| id | doaj.art-2d121940a0344d1dbb861867ed052a65 |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-04-09T14:25:52Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-2d121940a0344d1dbb861867ed052a652023-05-04T04:14:59ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122023-05-011410.3389/fphar.2023.11825711182571P-glycoprotein efflux transporter: a key to pharmacokinetic modeling for methadone clearance in fetusesHarvey Ho0En Zhang1Auckland Bioengineering Institute, The University of Auckland, Auckland, New ZealandChongqing Food and Drug Control Institute, Chongqing, Chinahttps://www.frontiersin.org/articles/10.3389/fphar.2023.1182571/fullmethadoneopioidsPBPKP-glycoproteinmodel |
| spellingShingle | Harvey Ho En Zhang P-glycoprotein efflux transporter: a key to pharmacokinetic modeling for methadone clearance in fetuses Frontiers in Pharmacology methadone opioids PBPK P-glycoprotein model |
| title | P-glycoprotein efflux transporter: a key to pharmacokinetic modeling for methadone clearance in fetuses |
| title_full | P-glycoprotein efflux transporter: a key to pharmacokinetic modeling for methadone clearance in fetuses |
| title_fullStr | P-glycoprotein efflux transporter: a key to pharmacokinetic modeling for methadone clearance in fetuses |
| title_full_unstemmed | P-glycoprotein efflux transporter: a key to pharmacokinetic modeling for methadone clearance in fetuses |
| title_short | P-glycoprotein efflux transporter: a key to pharmacokinetic modeling for methadone clearance in fetuses |
| title_sort | p glycoprotein efflux transporter a key to pharmacokinetic modeling for methadone clearance in fetuses |
| topic | methadone opioids PBPK P-glycoprotein model |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2023.1182571/full |
| work_keys_str_mv | AT harveyho pglycoproteineffluxtransporterakeytopharmacokineticmodelingformethadoneclearanceinfetuses AT enzhang pglycoproteineffluxtransporterakeytopharmacokineticmodelingformethadoneclearanceinfetuses |