Presenilin promotes dietary copper uptake.

Presenilin promotes dietary copper uptake.

Dietary copper is essential for multicellular organisms. Copper is redox active and required as a cofactor for enzymes such as the antioxidant Superoxide Dismutase 1 (SOD1). Copper dyshomeostasis has been implicated in Alzheimer's disease. Mutations in the presenilin genes encoding PS1 and PS2...

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Bibliographic Details
Main Authors:	Adam Southon, Mark A Greenough, George Ganio, Ashley I Bush, Richard Burke, James Camakaris
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3646984?pdf=render

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