Antioxidant activity of Haloxylon scoparium alkaloid extracts from Figuig region (southeastern of Morocco)
Abstract The aim of this paper is to study the chemical composition of alkaloids present in Haloxylon scoparium Pomel extracts and to evaluate their antioxidant capacity. The alkaloids were isolated from two parts of Haloxylon scoparium plant by two extraction protocols. and The quantitative study m...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Universidade de São Paulo
2022-06-01
|
| Series: | Brazilian Journal of Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100594&tlng=en |
| _version_ | 1818244392878604288 |
|---|---|
| author | Sara Haida Abdelaziz Kribii Naima Ait Daoud Rida Allah Belakhmima Abderahim Kribii |
| author_facet | Sara Haida Abdelaziz Kribii Naima Ait Daoud Rida Allah Belakhmima Abderahim Kribii |
| author_sort | Sara Haida |
| collection | DOAJ |
| description | Abstract The aim of this paper is to study the chemical composition of alkaloids present in Haloxylon scoparium Pomel extracts and to evaluate their antioxidant capacity. The alkaloids were isolated from two parts of Haloxylon scoparium plant by two extraction protocols. and The quantitative study made it possible to propose the best protocol for the extraction of the alkaloids. Moreover, GC-MS analysis of alkaloid extracts allowed us to determine their chemical composition. Haloxylon scoparium contains four types of alkaloids: tetraisoquinolines, phenylethylamines, tryptolines and tryptamines. The main compounds are the tetraisoquinolines type, the predominant product of which was N-methylsalsoline. These compounds present a great interest for the researchers due to their various pharmacological and biological activities. The antioxidant effect of the different plant extracts was studied by two methods: the ferric reducing antioxidant power (FRAP) and 1,1-diphenyl-2-picryl hydrazyl free radical (DPPH·) scavenging tests. The results show that extracts of root part are more active than those from aerial part; the acetone/water extract is the most powerful. The interesting results obtained in this study will be supplemented by other analyses and biological tests in order to better valorize this plant. |
| first_indexed | 2024-12-12T14:16:18Z |
| format | Article |
| id | doaj.art-2d12dbd4b94e497081db5f14af94505a |
| institution | Directory Open Access Journal |
| issn | 2175-9790 |
| language | English |
| last_indexed | 2024-12-12T14:16:18Z |
| publishDate | 2022-06-01 |
| publisher | Universidade de São Paulo |
| record_format | Article |
| series | Brazilian Journal of Pharmaceutical Sciences |
| spelling | doaj.art-2d12dbd4b94e497081db5f14af94505a2022-12-22T00:21:54ZengUniversidade de São PauloBrazilian Journal of Pharmaceutical Sciences2175-97902022-06-015810.1590/s2175-97902022e19494Antioxidant activity of Haloxylon scoparium alkaloid extracts from Figuig region (southeastern of Morocco)Sara Haidahttps://orcid.org/0000-0001-8776-8239Abdelaziz KribiiNaima Ait DaoudRida Allah BelakhmimaAbderahim KribiiAbstract The aim of this paper is to study the chemical composition of alkaloids present in Haloxylon scoparium Pomel extracts and to evaluate their antioxidant capacity. The alkaloids were isolated from two parts of Haloxylon scoparium plant by two extraction protocols. and The quantitative study made it possible to propose the best protocol for the extraction of the alkaloids. Moreover, GC-MS analysis of alkaloid extracts allowed us to determine their chemical composition. Haloxylon scoparium contains four types of alkaloids: tetraisoquinolines, phenylethylamines, tryptolines and tryptamines. The main compounds are the tetraisoquinolines type, the predominant product of which was N-methylsalsoline. These compounds present a great interest for the researchers due to their various pharmacological and biological activities. The antioxidant effect of the different plant extracts was studied by two methods: the ferric reducing antioxidant power (FRAP) and 1,1-diphenyl-2-picryl hydrazyl free radical (DPPH·) scavenging tests. The results show that extracts of root part are more active than those from aerial part; the acetone/water extract is the most powerful. The interesting results obtained in this study will be supplemented by other analyses and biological tests in order to better valorize this plant.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100594&tlng=enHaloxylon scopariumAlkaloidsExtractGC-MS analysisDPPHFRAP |
| spellingShingle | Sara Haida Abdelaziz Kribii Naima Ait Daoud Rida Allah Belakhmima Abderahim Kribii Antioxidant activity of Haloxylon scoparium alkaloid extracts from Figuig region (southeastern of Morocco) Brazilian Journal of Pharmaceutical Sciences Haloxylon scoparium Alkaloids Extract GC-MS analysis DPPH FRAP |
| title | Antioxidant activity of Haloxylon scoparium alkaloid extracts from Figuig region (southeastern of Morocco) |
| title_full | Antioxidant activity of Haloxylon scoparium alkaloid extracts from Figuig region (southeastern of Morocco) |
| title_fullStr | Antioxidant activity of Haloxylon scoparium alkaloid extracts from Figuig region (southeastern of Morocco) |
| title_full_unstemmed | Antioxidant activity of Haloxylon scoparium alkaloid extracts from Figuig region (southeastern of Morocco) |
| title_short | Antioxidant activity of Haloxylon scoparium alkaloid extracts from Figuig region (southeastern of Morocco) |
| title_sort | antioxidant activity of haloxylon scoparium alkaloid extracts from figuig region southeastern of morocco |
| topic | Haloxylon scoparium Alkaloids Extract GC-MS analysis DPPH FRAP |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100594&tlng=en |
| work_keys_str_mv | AT sarahaida antioxidantactivityofhaloxylonscopariumalkaloidextractsfromfiguigregionsoutheasternofmorocco AT abdelazizkribii antioxidantactivityofhaloxylonscopariumalkaloidextractsfromfiguigregionsoutheasternofmorocco AT naimaaitdaoud antioxidantactivityofhaloxylonscopariumalkaloidextractsfromfiguigregionsoutheasternofmorocco AT ridaallahbelakhmima antioxidantactivityofhaloxylonscopariumalkaloidextractsfromfiguigregionsoutheasternofmorocco AT abderahimkribii antioxidantactivityofhaloxylonscopariumalkaloidextractsfromfiguigregionsoutheasternofmorocco |