Effects of Sirt1 on proliferation, migration, and apoptosis of endothelial progenitor cells in peripheral blood of SD rats with chronic obstructive pulmonary disease

Effects of Sirt1 on proliferation, migration, and apoptosis of endothelial progenitor cells in peripheral blood of SD rats with chronic obstructive pulmonary disease

Objective: To explore the effect of Sirt1 on the function of endothelial progenitor cells (EPCs) in rats with chronic obstructive pulmonary disease (COPD). Methods: A rat COPD model was established via smoking and endotoxin administration for three months. The peripheral circulating EPCs were isolat...

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Bibliographic Details
Main Authors: Dong-Mei Sun, Jin-Jian Yao, Zhan-Ling Dong, Jin Qian, Qi-Feng Huang, Yuan-Tian Sun, Xiao-Ran Liu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
chronic obstructive pulmonary disease; endothelial progenitor cells; sirt1; proliferation; migration; adhesion; apoptosis; foxo3a; nf-κb; p53; rat
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2021;volume=11;issue=10;spage=429;epage=439;aulast=Sun

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http://www.apjtb.org/article.asp?issn=2221-1691;year=2021;volume=11;issue=10;spage=429;epage=439;aulast=Sun

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