Horizontally acquired papGII-containing pathogenicity islands underlie the emergence of invasive uropathogenic Escherichia coli lineages
Escherichia coli is a major cause of urinary tract infection. Here, Biggel et al. provide a phylogenomic analysis of 907 clinical E. coli isolates and identify the P-fimbriae-encoding locus associated with invasive uropathogenic E. coli isolates.
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2020-11-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-19714-9 |
| _version_ | 1818735326590402560 |
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| author | Michael Biggel Basil B. Xavier James R. Johnson Karen L. Nielsen Niels Frimodt-Møller Veerle Matheeussen Herman Goossens Pieter Moons Sandra Van Puyvelde |
| author_facet | Michael Biggel Basil B. Xavier James R. Johnson Karen L. Nielsen Niels Frimodt-Møller Veerle Matheeussen Herman Goossens Pieter Moons Sandra Van Puyvelde |
| author_sort | Michael Biggel |
| collection | DOAJ |
| description | Escherichia coli is a major cause of urinary tract infection. Here, Biggel et al. provide a phylogenomic analysis of 907 clinical E. coli isolates and identify the P-fimbriae-encoding locus associated with invasive uropathogenic E. coli isolates. |
| first_indexed | 2024-12-18T00:19:29Z |
| format | Article |
| id | doaj.art-2d1f35146af84c69957aabe9baab7724 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-18T00:19:29Z |
| publishDate | 2020-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-2d1f35146af84c69957aabe9baab77242022-12-21T21:27:23ZengNature PortfolioNature Communications2041-17232020-11-0111111510.1038/s41467-020-19714-9Horizontally acquired papGII-containing pathogenicity islands underlie the emergence of invasive uropathogenic Escherichia coli lineagesMichael Biggel0Basil B. Xavier1James R. Johnson2Karen L. Nielsen3Niels Frimodt-Møller4Veerle Matheeussen5Herman Goossens6Pieter Moons7Sandra Van Puyvelde8Laboratory of Medical Microbiology, Vaccine and Infectious Disease Institute, University of AntwerpLaboratory of Medical Microbiology, Vaccine and Infectious Disease Institute, University of AntwerpVeterans Affairs Medical Center and University of MinnesotaDepartment of Clinical Microbiology, RigshospitaletDepartment of Clinical Microbiology, RigshospitaletLaboratory of Medical Microbiology, Vaccine and Infectious Disease Institute, University of AntwerpLaboratory of Medical Microbiology, Vaccine and Infectious Disease Institute, University of AntwerpLaboratory of Medical Microbiology, Vaccine and Infectious Disease Institute, University of AntwerpLaboratory of Medical Microbiology, Vaccine and Infectious Disease Institute, University of AntwerpEscherichia coli is a major cause of urinary tract infection. Here, Biggel et al. provide a phylogenomic analysis of 907 clinical E. coli isolates and identify the P-fimbriae-encoding locus associated with invasive uropathogenic E. coli isolates.https://doi.org/10.1038/s41467-020-19714-9 |
| spellingShingle | Michael Biggel Basil B. Xavier James R. Johnson Karen L. Nielsen Niels Frimodt-Møller Veerle Matheeussen Herman Goossens Pieter Moons Sandra Van Puyvelde Horizontally acquired papGII-containing pathogenicity islands underlie the emergence of invasive uropathogenic Escherichia coli lineages Nature Communications |
| title | Horizontally acquired papGII-containing pathogenicity islands underlie the emergence of invasive uropathogenic Escherichia coli lineages |
| title_full | Horizontally acquired papGII-containing pathogenicity islands underlie the emergence of invasive uropathogenic Escherichia coli lineages |
| title_fullStr | Horizontally acquired papGII-containing pathogenicity islands underlie the emergence of invasive uropathogenic Escherichia coli lineages |
| title_full_unstemmed | Horizontally acquired papGII-containing pathogenicity islands underlie the emergence of invasive uropathogenic Escherichia coli lineages |
| title_short | Horizontally acquired papGII-containing pathogenicity islands underlie the emergence of invasive uropathogenic Escherichia coli lineages |
| title_sort | horizontally acquired papgii containing pathogenicity islands underlie the emergence of invasive uropathogenic escherichia coli lineages |
| url | https://doi.org/10.1038/s41467-020-19714-9 |
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