Spatial Configurations of 3D Extracellular Matrix Collagen Density and Anisotropy Simultaneously Guide Angiogenesis.

Spatial Configurations of 3D Extracellular Matrix Collagen Density and Anisotropy Simultaneously Guide Angiogenesis.

Extracellular matrix (ECM) collagen density and fibril anisotropy are thought to affect the development of new vasculatures during pathologic and homeostatic angiogenesis. Computational simulation is emerging as a tool to investigate the role of matrix structural configurations on cell guidance. How...

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Bibliographic Details
Main Authors: Steven A LaBelle, A Marsh Poulson, Steve A Maas, Adam Rauff, Gerard A Ateshian, Jeffrey A Weiss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-10-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011553&type=printable

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