Raynaud's phenomenon of the nipple as a side-effect of labetalol: Case report and literature review

Raynaud's phenomenon of the nipple is an unusual side-effect of labetalol use. There is one official report from the United Kingdom. The present case concerns a 30-year-old woman, gravida 1, para 0, who developed pre-eclampsia and was treated with labetalol but subsequently reported neuropathic...

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Main Authors: Jesus Avila-Vega, Enrique Urrea-Mendoza, Christy Lee
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Case Reports in Women's Health
Online Access:http://www.sciencedirect.com/science/article/pii/S221491121930116X
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author Jesus Avila-Vega
Enrique Urrea-Mendoza
Christy Lee
author_facet Jesus Avila-Vega
Enrique Urrea-Mendoza
Christy Lee
author_sort Jesus Avila-Vega
collection DOAJ
description Raynaud's phenomenon of the nipple is an unusual side-effect of labetalol use. There is one official report from the United Kingdom. The present case concerns a 30-year-old woman, gravida 1, para 0, who developed pre-eclampsia and was treated with labetalol but subsequently reported neuropathic pain of the nipple. Nifedipine was then started as part of her treatment plan for blood pressure control and she no longer reported pain, despite being given six more doses of labetalol. Nifedipine is the first-line of treatment for Raynaud's phenomenon. The concomitant use of labetalol with nifedipine by a woman with Raynaud's phenomenon of the nipple has not been discussed before. The goal of this review is to raise awareness of this drug-induced phenomenon and to add to the limited literature available on this subject. Keywords: Raynaud's phenomenon, Nipple pain, Labetalol, Nifedipine, Neuropathic pain, Pre-eclampsia
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spelling doaj.art-2d20baf55fe44ebab5cfc8a6722618aa2022-12-21T23:55:29ZengElsevierCase Reports in Women's Health2214-91122019-07-0123Raynaud's phenomenon of the nipple as a side-effect of labetalol: Case report and literature reviewJesus Avila-Vega0Enrique Urrea-Mendoza1Christy Lee2School of Medicine, University of South Carolina, Greenville, SC, USACLEMSON School of Health Research, Professor School of Medicine University of South Carolina, Neuroscience Associates, PRISMA Health-Upstate, Greenville, SC, USA; Corresponding author at: Neuroscience Associates, PRISMA Health-Upstate, 200 Patewood Dr. B 350, Greenville, SC 29615, USA.Obstetrician-gynecologist, School of Medicine; University of South Carolina, Prisma Health-Upstate, Greenville, SC, USARaynaud's phenomenon of the nipple is an unusual side-effect of labetalol use. There is one official report from the United Kingdom. The present case concerns a 30-year-old woman, gravida 1, para 0, who developed pre-eclampsia and was treated with labetalol but subsequently reported neuropathic pain of the nipple. Nifedipine was then started as part of her treatment plan for blood pressure control and she no longer reported pain, despite being given six more doses of labetalol. Nifedipine is the first-line of treatment for Raynaud's phenomenon. The concomitant use of labetalol with nifedipine by a woman with Raynaud's phenomenon of the nipple has not been discussed before. The goal of this review is to raise awareness of this drug-induced phenomenon and to add to the limited literature available on this subject. Keywords: Raynaud's phenomenon, Nipple pain, Labetalol, Nifedipine, Neuropathic pain, Pre-eclampsiahttp://www.sciencedirect.com/science/article/pii/S221491121930116X
spellingShingle Jesus Avila-Vega
Enrique Urrea-Mendoza
Christy Lee
Raynaud's phenomenon of the nipple as a side-effect of labetalol: Case report and literature review
Case Reports in Women's Health
title Raynaud's phenomenon of the nipple as a side-effect of labetalol: Case report and literature review
title_full Raynaud's phenomenon of the nipple as a side-effect of labetalol: Case report and literature review
title_fullStr Raynaud's phenomenon of the nipple as a side-effect of labetalol: Case report and literature review
title_full_unstemmed Raynaud's phenomenon of the nipple as a side-effect of labetalol: Case report and literature review
title_short Raynaud's phenomenon of the nipple as a side-effect of labetalol: Case report and literature review
title_sort raynaud s phenomenon of the nipple as a side effect of labetalol case report and literature review
url http://www.sciencedirect.com/science/article/pii/S221491121930116X
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AT christylee raynaudsphenomenonofthenippleasasideeffectoflabetalolcasereportandliteraturereview