378 Regulation of renal function by the peroxisome proliferator-activated receptor-alpha: A novel target for treating hypertension
OBJECTIVES/GOALS: Approximately 37 million people in the U.S. have chronic kidney disease, which is a major risk factor for cardiovascular and end stage renal diseases. PPAR-αknockout (KO) mice exhibit increased renal inflammation and blood pressure. In this study, we investigated the role of PPAR-...
Main Authors: | Mark D Hatcher, Kathryn Sandberg, Dexter Lee |
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Format: | Article |
Language: | English |
Published: |
Cambridge University Press
2023-04-01
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Series: | Journal of Clinical and Translational Science |
Online Access: | https://www.cambridge.org/core/product/identifier/S2059866123004156/type/journal_article |
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