A Method to Constrain Genome-Scale Models with 13C Labeling Data.

Current limitations in quantitatively predicting biological behavior hinder our efforts to engineer biological systems to produce biofuels and other desired chemicals. Here, we present a new method for calculating metabolic fluxes, key targets in metabolic engineering, that incorporates data from 13...

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Bibliographic Details
Main Authors: Héctor García Martín, Vinay Satish Kumar, Daniel Weaver, Amit Ghosh, Victor Chubukov, Aindrila Mukhopadhyay, Adam Arkin, Jay D Keasling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-09-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4574858?pdf=render

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