A Method to Constrain Genome-Scale Models with 13C Labeling Data.
Current limitations in quantitatively predicting biological behavior hinder our efforts to engineer biological systems to produce biofuels and other desired chemicals. Here, we present a new method for calculating metabolic fluxes, key targets in metabolic engineering, that incorporates data from 13...
Main Authors: | Héctor García Martín, Vinay Satish Kumar, Daniel Weaver, Amit Ghosh, Victor Chubukov, Aindrila Mukhopadhyay, Adam Arkin, Jay D Keasling |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-09-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC4574858?pdf=render |
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