Effects of phorbol 12-myristate 13-acetate on triglyceride and cholesteryl ester synthesis in cultured coronary smooth muscle cells and macrophages.

Effects of phorbol 12-myristate 13-acetate on triglyceride and cholesteryl ester synthesis in cultured coronary smooth muscle cells and macrophages.

In cultured pig coronary smooth muscle cells phorbol 12-myristate 13-acetate (PMA) stimulated the conversion of [4-14C]cholesterol into cholesteryl esters and the incorporation of [2-3H]glycerol into triglycerides 6.4- and 4.5-fold, respectively. The maximal effects occurred after 3 h of treatment a...

Full description

Bibliographic Details
Main Authors:	M Moinat, JM Chevey, P Muzzin, JP Giacobino, M Kossovsky
Format:	Article
Language:	English
Published:	Elsevier 1990-02-01
Series:	Journal of Lipid Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520432183

Similar Items

Neutrophil Activated by the Famous and Potent PMA (Phorbol Myristate Acetate)
by: Hylane Luiz Damascena, et al.
Published: (2022-09-01)

A Comparison Between Phorbol 12 Myristate 13 Acetate and Phorbol 12, 13 Dibutyrate in Human Melanocyte Culture
by: Divya Padma, et al.
Published: (2016-01-01)

Effect of phorbol 12-myristate 13-acetate treatment on choline kinase expression
by: Seong, Chan Ying
Published: (2012)

Interactions of cholesterol esters with phospholipids: cholesteryl myristate and dimyristoyl lecithin.
by: M J Janiak, et al.
Published: (1979-02-01)

Nanomechanical measurement of adhesion and migration of leukemia cells with phorbol 12-myristate 13-acetate treatment
by: Zhou ZL, et al.
Published: (2016-12-01)

Effects of phorbol myristate acetate and sivelestat on the lung injury caused by fat embolism in isolated lungs
by: Lin Chia-Chih, et al.
Published: (2012-01-01)

"The adherence and functional properties of mice peritoneal macrophage phagocytic system with Phorbol Myristate Acetate stimulation and Nitroblue Tetrazolium reduction assay "
by: Mosaffa N, et al.
Published: (2002-11-01)

Comparative Proteomic Analysis Reveals Varying Impact on Immune Responses in Phorbol 12-Myristate-13-Acetate-Mediated THP-1 Monocyte-to-Macrophage Differentiation
by: Sneha M. Pinto, et al.
Published: (2021-06-01)

Cytoskeletal Responses and Aif-1 Expression in Caco-2 Monolayers Exposed to Phorbol-12-Myristate-13-Acetate and Carnosine
by: Aurora Mazzei, et al.
Published: (2022-12-01)

Phorbol-12-myristate-13-acetate is a potent enhancer of B cells with a granzyme B+ regulatory phenotype
by: Johanna Veh, et al.
Published: (2023-07-01)

Effect of sphingosine and phorbol-12-myristate-13-acetate on the growth and dimethylsulfoxide-induced differentiation in the insect trypanosomatid Herpetomonas samuelpessoai
by: André Luis Souza dos Santos, et al.
Published: (2007-08-01)

(+)-Borneol inhibits the generation of reactive oxygen species and neutrophil extracellular traps induced by phorbol-12-myristate-13-acetate
by: Hanze Chen, et al.
Published: (2022-11-01)

Geraniol suppresses proinflammatory mediators in phorbol 12-myristate 13-acetate with A23187-induced HMC-1 cells
by: Huang Y, et al.
Published: (2018-09-01)

Triglyceride alters lysosomal cholesterol ester metabolism in cholesteryl ester-laden macrophage foam cells[S]
by: Jody C. Ullery-Ricewick, et al.
Published: (2009-10-01)

Micromanipulation of adhesion of phorbol 12-myristate-13-acetate-stimulated T lymphocytes to planar membranes containing intercellular adhesion molecule-1.
by: Tözeren, A, et al.
Published: (1992)

Sustained small and intermediate size proteins expression in phorbol 12-myristate 13-acetate/ionomycine prolonged stimulated human fibroblasts
by: Zeinab Abedian, et al.
Published: (2017-05-01)

Induction of nerve growth factor by phorbol 12-myristate 13-acetate is dependent upon the mitogen activated protein kinase pathway
by: Justin B. Davis, et al.
Published: (2018-05-01)

Triglyceride and cholesteryl ester hydrolysis in a cell culture model of smooth muscle foam cells.
by: L K Minor, et al.
Published: (1989-02-01)

Resting time after phorbol 12-myristate 13-acetate in THP-1 derived macrophages provides a non-biased model for the study of NLRP3 inflammasome
by: Sonia Giambelluca, et al.
Published: (2022-12-01)

NRF2 Signaling Negatively Regulates Phorbol-12-Myristate-13-Acetate (PMA)-Induced Differentiation of Human Monocytic U937 Cells into Pro-Inflammatory Macrophages.
by: Min-Gu Song, et al.
Published: (2015-01-01)

Bioinformatics of Differentially Expressed Genes in Phorbol 12-Myristate 13-Acetate-Induced Megakaryocytic Differentiation of K562 Cells by Microarray Analysis
by: Seung-Hoon Lee, et al.
Published: (2022-04-01)

Phorbol myristate acetate suppresses breast cancer cell growth via down-regulation of P-Rex1 expression
by: Chuu-Yun A. Wong, et al.
Published: (2016-03-01)

Thermotropic mesomorphism of cholesteryl myristate. An electron diffraction study.
by: D L Dorset
Published: (1985-09-01)

REGULATION OF TLR/RLR GENE ACTIVITY AND SYNTHESIS OF CYTOKINES DURING PHORBOL MYRISTATE ACETATE (PMA)-INDUCED DIFFERENTIATION OF THP-1 MONOCYTES INTO MACROPHAGE-LIKE CELLS
by: T. M. Sokolova, et al.
Published: (2017-01-01)

<i>Piper sarmentosum</i> Roxb. Inhibits Angiotensin-Converting Enzyme Activity in Phorbol 12-Myristate-13-Acetate-Induced Endothelial Cells
by: Azizah Ugusman, et al.
Published: (2024-02-01)

Phorbol 12-Myristate 13-Acetate Induces MUC16 Expression via PKCδ and p38 in Human Airway Epithelial Cells
by: Chang Hoon Bae, et al.
Published: (2012-09-01)

Evaluation of effects of various drugs on platelet functions using phorbol 12-myristate 13-acetate-induced megakaryocytic human erythroid leukemia cells
by: Tada T, et al.
Published: (2016-09-01)

Accumulation and mobilization of triglycerides and cholesteryl esters in Leydig tumor cells.
by: DA Freeman, et al.
Published: (1992-08-01)

Critical role of neutral cholesteryl ester hydrolase 1 in cholesteryl ester hydrolysis in murine macrophages[S]
by: Kent Sakai, et al.
Published: (2014-10-01)

"Slow" Voltage-Dependent Inactivation of CaV2.2 Calcium Channels Is Modulated by the PKC Activator Phorbol 12-Myristate 13-Acetate (PMA).
by: Lei Zhu, et al.
Published: (2015-01-01)

Effect of Dark Chocolate Extracts on Phorbol 12-Myristate 13-Acetate-Induced Oxidative Burst in Leukocytes Isolated by Normo-Weight and Overweight/Obese Subjects
by: Francesca Ioannone, et al.
Published: (2017-06-01)

Phorbol 12-Myristate 13-Acetate Induced Toxicity Study and the Role of Tangeretin in Abrogating HIF-1α-NF-κB Crosstalk In Vitro and In Vivo
by: Sukkum Ngullie Chang, et al.
Published: (2020-12-01)

Forskolin and Phorbol 12-myristate 13-acetate modulates the expression pattern of AP-1 factors and cell cycle regulators in estrogen-responsive MCF-7 cells
by: R.L. Babu, et al.
Published: (2019-06-01)

Effect of differentiating agents (all-trans retinoic acid and phorbol 12-myristate 13-acetate) on drug sensitivity of HL60 and NB4 cells in vitro.
by: Jadwiga Mirecka, et al.
Published: (2008-12-01)

Establishment of the Reference Intervals of Lymphocyte Function in Healthy Adults Based on IFN-γ Secretion Assay upon Phorbol-12-Myristate-13-Acetate/Ionomycin Stimulation
by: Hongyan Hou, et al.
Published: (2018-02-01)

Phorbol-12-myristate 13-acetate inhibits Nephronectin gene expression via Protein kinase C alpha and c-Jun/c-Fos transcription factors
by: Mitsuhiro Kinoshita, et al.
Published: (2021-10-01)

Effect of phosphatidylcholine molecular species on the uptake of HDL triglycerides and cholesteryl esters by the liver.
by: H Kadowaki, et al.
Published: (1993-02-01)

Light induced degradation of phorbol esters
by: Yunping, Bu, et al.
Published: (2013)

Production of Biodiesel Fuel and Reduction of Phorbol Esters by Transesterification of Jatropha Curcas Oil with Methyl Acetate
by: Tomoki Terawaki, et al.
Published: (2020-06-01)

Triglyceride enrichment of HDL does not alter HDL-selective cholesteryl ester clearance in rabbits
by: Shirya Rashid, et al.
Published: (2001-02-01)