Indirect spectrophotometric determination of Cephalexin and paracetamol by Cu-NTA complex in aqueous solution
A spectrophotometric method has been described for the determination of cephalexin and paracetamol by their reaction with Cu-NTA complex in aqueous solution leading to increase the complex absorbance at Xmax=832 nra from which the excess absorbance is measured. Beer's law is obeyed over the con...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Arabic |
| Published: |
College of Education for Pure Sciences
2005-06-01
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| Series: | مجلة التربية والعلم |
| Subjects: | |
| Online Access: | https://edusj.mosuljournals.com/article_82404_1a7bf08c973554172a724c1bc9fc29c1.pdf |
| _version_ | 1819017079895883776 |
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| author | Thabit Al-Ghabsha Theiaa Al-Sabha Amal Saeed |
| author_facet | Thabit Al-Ghabsha Theiaa Al-Sabha Amal Saeed |
| author_sort | Thabit Al-Ghabsha |
| collection | DOAJ |
| description | A spectrophotometric method has been described for the determination of cephalexin and paracetamol by their reaction with Cu-NTA complex in aqueous solution leading to increase the complex absorbance at Xmax=832 nra from which the excess absorbance is measured. Beer's law is obeyed over the concentration range of 0.05-3.20 ppt for cephalexin and 0.20-2.75 mg/ml for paracetamol. The average recoveries are 97.13% and 98.03% for the above drugs respectively, and precision (RSD) is found to be better than 4% for both drugs. The method has been applied successfully for determination of the above drugs in some of their pharmaceutical preparations. The results obtained are in agreement with their certified values and also with standard addition procedure. |
| first_indexed | 2024-12-21T02:57:50Z |
| format | Article |
| id | doaj.art-2d2483b5228d4f56a5e210d2cc4f11da |
| institution | Directory Open Access Journal |
| issn | 1812-125X 2664-2530 |
| language | Arabic |
| last_indexed | 2024-12-21T02:57:50Z |
| publishDate | 2005-06-01 |
| publisher | College of Education for Pure Sciences |
| record_format | Article |
| series | مجلة التربية والعلم |
| spelling | doaj.art-2d2483b5228d4f56a5e210d2cc4f11da2022-12-21T19:18:16ZaraCollege of Education for Pure Sciencesمجلة التربية والعلم1812-125X2664-25302005-06-0117311510.33899/edusj.2005.8240482404Indirect spectrophotometric determination of Cephalexin and paracetamol by Cu-NTA complex in aqueous solutionThabit Al-GhabshaTheiaa Al-SabhaAmal SaeedA spectrophotometric method has been described for the determination of cephalexin and paracetamol by their reaction with Cu-NTA complex in aqueous solution leading to increase the complex absorbance at Xmax=832 nra from which the excess absorbance is measured. Beer's law is obeyed over the concentration range of 0.05-3.20 ppt for cephalexin and 0.20-2.75 mg/ml for paracetamol. The average recoveries are 97.13% and 98.03% for the above drugs respectively, and precision (RSD) is found to be better than 4% for both drugs. The method has been applied successfully for determination of the above drugs in some of their pharmaceutical preparations. The results obtained are in agreement with their certified values and also with standard addition procedure.https://edusj.mosuljournals.com/article_82404_1a7bf08c973554172a724c1bc9fc29c1.pdfcephalexinparacetamolcopper-nitrile acetic |
| spellingShingle | Thabit Al-Ghabsha Theiaa Al-Sabha Amal Saeed Indirect spectrophotometric determination of Cephalexin and paracetamol by Cu-NTA complex in aqueous solution مجلة التربية والعلم cephalexin paracetamol copper-nitrile acetic |
| title | Indirect spectrophotometric determination of Cephalexin and paracetamol by Cu-NTA complex in aqueous solution |
| title_full | Indirect spectrophotometric determination of Cephalexin and paracetamol by Cu-NTA complex in aqueous solution |
| title_fullStr | Indirect spectrophotometric determination of Cephalexin and paracetamol by Cu-NTA complex in aqueous solution |
| title_full_unstemmed | Indirect spectrophotometric determination of Cephalexin and paracetamol by Cu-NTA complex in aqueous solution |
| title_short | Indirect spectrophotometric determination of Cephalexin and paracetamol by Cu-NTA complex in aqueous solution |
| title_sort | indirect spectrophotometric determination of cephalexin and paracetamol by cu nta complex in aqueous solution |
| topic | cephalexin paracetamol copper-nitrile acetic |
| url | https://edusj.mosuljournals.com/article_82404_1a7bf08c973554172a724c1bc9fc29c1.pdf |
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