A Rare Cause of Acute Renal Failure: Fenofibrate-Induced Rhabdomyolysis

Fibrates are derivative of fibric acid and broad spectrum drugs which are commonly used in the treatment of dyslipidemia and hypertriglyceridemia. Side effects are often related with striated muscles, kidney and liver. Rhabdomyolysis developing with striated muscle destruction is potentially the mos...

Full description

Bibliographic Details
Main Authors: Ferhat Icme, Tugba Temrel, Havva Sahin Kavakli, Yucel Yuzbasioglu, Gulhan Kurtoglu Celik, Zeynep Saral Ozturk
Format: Article
Language:English
Published: Cukurova University 2013-08-01
Series:Çukurova Üniversitesi Tıp Fakültesi Dergisi
Subjects:
Online Access:http://www.scopemed.org/fulltextpdf.php?mno=35993
Description
Summary:Fibrates are derivative of fibric acid and broad spectrum drugs which are commonly used in the treatment of dyslipidemia and hypertriglyceridemia. Side effects are often related with striated muscles, kidney and liver. Rhabdomyolysis developing with striated muscle destruction is potentially the most lethal of these side effects. Although several case reports of rhabdomyolysis have been reported due to the combination of statin and fenofibrate, fenofibrate alone rarely causes rhabdomyolysis. The purposes of this paper are to present a patient whom we diagnosed with acute renal injury due to use of fenofibrate in order to emphasize the importance of questioning drugs which have been used, and to review management of rhabdomyolysis due to fenofibrate use. [Cukurova Med J 2013; 38(4.000): 800-804]
ISSN:0250-5150