Correlation of ultrasound measurement of limb muscle thickness and echo intensity with frailty assessment in elderly patients undergoing malignancies surgery
Introduction: It remains controversial which frailty score correlates with adverse outcomes. Instead of these subjective and time consuming scores, we studied whether ultrasound guided lower extremity thickness measurements more closely are associated with adverse outcomes. Method: Patients undergoi...
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Elsevier
2024-01-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024000483 |
| _version_ | 1797336880859054080 |
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| author | Chengjian Xin Mengzhuo Ma Qian Wang Tao Li Qiaoxia Sun Meiru Jiang Juan Du Zhi Li Jiahai Ma |
| author_facet | Chengjian Xin Mengzhuo Ma Qian Wang Tao Li Qiaoxia Sun Meiru Jiang Juan Du Zhi Li Jiahai Ma |
| author_sort | Chengjian Xin |
| collection | DOAJ |
| description | Introduction: It remains controversial which frailty score correlates with adverse outcomes. Instead of these subjective and time consuming scores, we studied whether ultrasound guided lower extremity thickness measurements more closely are associated with adverse outcomes. Method: Patients undergoing gastrointestinal malignancy surgery were included as study subjects. Frailty was identified using the FRAIL scale assessment. Ultrasound measured the muscle thickness and echo intensity of the patient's upper and lower limbs. ANOVA was used to analyze the relationship between muscle data and frailty assessment. Significant indicators from the one-way analysis were included in the multivariate logistic regression equation. Results: A total of 160 study subjects were included, 52 in the normal group, 78 in the prefrailty group, and 30 in the frailty group. The ANOVA showed that there were significant differences in age, hemoglobin, albumin, history of hypertension, history of coronary artery disease, the history of cerebrovascular disease, rate of postoperative complications, rate of transferring to intensive care unit, time out of bed, length of hospitalization, thickness and echo intensity of quadriceps femoris the vastus lateralis and the tibialis anterior, echo intensity of the medial gastrocnemius among the three groups (P < 0.05). Pearson's correlation analysis showed FRAIL score was correlated with muscle thickness and echo intensity of the lower limbs. Multifactor logistic regression analysis showed that the prefrailty group was positively correlated with age（β = 0.146, P = 0.004）, echo intensity of the medial gastrocnemius (β = 0.055, P = 0.031), and rate of postoperative complications（β = 1.439, P = 0.021）, also negatively correlated with muscle thickness of the tibialis anterior（β = −2.124, P = 0.007）. The frailty group was positively correlated with age（β = 0.22, P = 0.005）, tibialis anterior echo intensity (β = 0.082, P = 0.015), medial gastrocnemius echo intensity (β = 0.089, P = 0.026), cerebrovascular disease history (β = 2.311, P = 0.04), and postoperative complication rate (β = 2.684, P = 0.003). It was negatively correlated with albumin (β = −0.26, P = 0.017), quadriceps muscle thickness (β = −2.257, P = 0.017), and tibialis anterior muscle thickness (β = −5.408, P = 0.001). Conclusion: Ultrasound measurement of lower (not upper) extremity muscle thickness and echo intensity was significantly associated with discriminating severity of frailty and postoperative outcomes than frailty scores in elderly patients. |
| first_indexed | 2024-03-08T09:01:20Z |
| format | Article |
| id | doaj.art-2d31cdad0fb04f5c8dbe428064b1d65c |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-08T09:01:20Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-2d31cdad0fb04f5c8dbe428064b1d65c2024-02-01T06:34:24ZengElsevierHeliyon2405-84402024-01-01101e24017Correlation of ultrasound measurement of limb muscle thickness and echo intensity with frailty assessment in elderly patients undergoing malignancies surgeryChengjian Xin0Mengzhuo Ma1Qian Wang2Tao Li3Qiaoxia Sun4Meiru Jiang5Juan Du6Zhi Li7Jiahai Ma8School of Anesthesiology, Weifang Medical University, Weifang, ChinaSchool of Clinical Medicine, Xi'an Medical University, Xi'an, ChinaDepartment of Anesthesia, Yuhuangding Hospital, Yantai, ChinaDepartment of Anesthesia, Yuhuangding Hospital, Yantai, ChinaDepartment of Anesthesia, Yuhuangding Hospital, Yantai, ChinaDepartment of Anesthesia, Yuhuangding Hospital, Yantai, ChinaDepartment of Anesthesia, Yuhuangding Hospital, Yantai, ChinaDepartment of Anesthesia, Yuhuangding Hospital, Yantai, ChinaDepartment of Anesthesia, Yuhuangding Hospital, Yantai, China; Corresponding author. Yuhuangding Hospital, Yantai, China.Introduction: It remains controversial which frailty score correlates with adverse outcomes. Instead of these subjective and time consuming scores, we studied whether ultrasound guided lower extremity thickness measurements more closely are associated with adverse outcomes. Method: Patients undergoing gastrointestinal malignancy surgery were included as study subjects. Frailty was identified using the FRAIL scale assessment. Ultrasound measured the muscle thickness and echo intensity of the patient's upper and lower limbs. ANOVA was used to analyze the relationship between muscle data and frailty assessment. Significant indicators from the one-way analysis were included in the multivariate logistic regression equation. Results: A total of 160 study subjects were included, 52 in the normal group, 78 in the prefrailty group, and 30 in the frailty group. The ANOVA showed that there were significant differences in age, hemoglobin, albumin, history of hypertension, history of coronary artery disease, the history of cerebrovascular disease, rate of postoperative complications, rate of transferring to intensive care unit, time out of bed, length of hospitalization, thickness and echo intensity of quadriceps femoris the vastus lateralis and the tibialis anterior, echo intensity of the medial gastrocnemius among the three groups (P < 0.05). Pearson's correlation analysis showed FRAIL score was correlated with muscle thickness and echo intensity of the lower limbs. Multifactor logistic regression analysis showed that the prefrailty group was positively correlated with age（β = 0.146, P = 0.004）, echo intensity of the medial gastrocnemius (β = 0.055, P = 0.031), and rate of postoperative complications（β = 1.439, P = 0.021）, also negatively correlated with muscle thickness of the tibialis anterior（β = −2.124, P = 0.007）. The frailty group was positively correlated with age（β = 0.22, P = 0.005）, tibialis anterior echo intensity (β = 0.082, P = 0.015), medial gastrocnemius echo intensity (β = 0.089, P = 0.026), cerebrovascular disease history (β = 2.311, P = 0.04), and postoperative complication rate (β = 2.684, P = 0.003). It was negatively correlated with albumin (β = −0.26, P = 0.017), quadriceps muscle thickness (β = −2.257, P = 0.017), and tibialis anterior muscle thickness (β = −5.408, P = 0.001). Conclusion: Ultrasound measurement of lower (not upper) extremity muscle thickness and echo intensity was significantly associated with discriminating severity of frailty and postoperative outcomes than frailty scores in elderly patients.http://www.sciencedirect.com/science/article/pii/S2405844024000483UltrasoundFrailtyElderlyMuscle thicknessEcho intensityPrognosis |
| spellingShingle | Chengjian Xin Mengzhuo Ma Qian Wang Tao Li Qiaoxia Sun Meiru Jiang Juan Du Zhi Li Jiahai Ma Correlation of ultrasound measurement of limb muscle thickness and echo intensity with frailty assessment in elderly patients undergoing malignancies surgery Heliyon Ultrasound Frailty Elderly Muscle thickness Echo intensity Prognosis |
| title | Correlation of ultrasound measurement of limb muscle thickness and echo intensity with frailty assessment in elderly patients undergoing malignancies surgery |
| title_full | Correlation of ultrasound measurement of limb muscle thickness and echo intensity with frailty assessment in elderly patients undergoing malignancies surgery |
| title_fullStr | Correlation of ultrasound measurement of limb muscle thickness and echo intensity with frailty assessment in elderly patients undergoing malignancies surgery |
| title_full_unstemmed | Correlation of ultrasound measurement of limb muscle thickness and echo intensity with frailty assessment in elderly patients undergoing malignancies surgery |
| title_short | Correlation of ultrasound measurement of limb muscle thickness and echo intensity with frailty assessment in elderly patients undergoing malignancies surgery |
| title_sort | correlation of ultrasound measurement of limb muscle thickness and echo intensity with frailty assessment in elderly patients undergoing malignancies surgery |
| topic | Ultrasound Frailty Elderly Muscle thickness Echo intensity Prognosis |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024000483 |
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