Homocysteine induces glyceraldehyde-3-phosphate dehydrogenase acetylation and apoptosis in the neuroblastoma cell line Neuro2a

High plasma levels of homocysteine (Hcy) promote the progression of neurodegenerative diseases. However, the mechanism by which Hcy mediates neurotoxicity has not been elucidated. We observed that upon incubation with Hcy, the viability of a neuroblastoma cell line Neuro2a declined in a dose-depende...

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Bibliographische Detailangaben
Hauptverfasser: M. Fang, A. Jin, Y. Zhao, X. Liu
Format: Artikel
Sprache:English
Veröffentlicht: Associação Brasileira de Divulgação Científica 2016-01-01
Schriftenreihe:Brazilian Journal of Medical and Biological Research
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Online Zugang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000200606&lng=en&tlng=en