Evaluation of Thrombocytopenia in Dengue Infection Along with Seasonal Variation in Rural Melmaruvathur
Introduction: Dengue is one of the most prevalent mosquitoborne arboviral infection in India. Seventy percent of the 96 million apparent infections occur in Asia, in which India is making upto one third of the total. Despite considerable efforts to control the mosquito populations, dengue fever h...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2014-01-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/3914/12-6739_E(C)_F(DK)_PF1(VP)_PFA(H)_PFA(AK)_PF2(RAK)_(NJH).pdf |
| Summary: | Introduction: Dengue is one of the most prevalent mosquitoborne arboviral infection in India. Seventy percent of the 96
million apparent infections occur in Asia, in which India is making
upto one third of the total. Despite considerable efforts to control
the mosquito populations, dengue fever has emerged, spread
and established itself rapidly. The most serious manifestations of
the infection are Dengue Hemorrhagic Fever (DHF) and Dengue
Shock Syndrome (DSS).
Objectives: Evaluation of thrombocytopenia in dengue infection
along with seasonal variation.
Material and Methods: The present study was conducted
retrospectively for a period of two years in Melmaruvathur from
January 2011 to December 2012. Blood samples were collected
from 1,464 patients experiencing febrile illness, clinically
consistent with dengue infection. Serological confirmation of
dengue infection and evaluation of platelet counts was done in
all the serologically positive cases.
Results: A total of 1,464 fever cases were admitted during the
study period and among them, 107 (7.3%) were found to be
seropositive for dengue. A majority, 41 (38.3%) of the dengue
cases was noted in the age group of 15-30 years, followed by less
than 15 years of age and the mean age of the seropositive cases was
29.78 ± 15.3 years. Among the dengue cases, 62.6% were males
and 37.4 % were females. A statistically significant association
(p<0.05) was found between the age groups and severity of
thrombocytopenia, between severity of thrombocytopenia
and clinical presentation of dengue infections. A significantly
higher number of serologically positive cases were noted, when
compared to serologically negative cases in the post monsoon
period.
Conclusion: This retrospective study highlighted significant
dengue infection during seasonal variation. The median age of
dengue patients has decreased and younger patients may be
more susceptible. |
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| ISSN: | 2249-782X 0973-709X |