Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid <i>T</i><sub>1</sub> Mapping Method
MRI-based gel dosimeters are attractive systems for the evaluation of complex dose distributions in radiotherapy. In particular, the nanocomposite Fricke gel dosimeter is one among a few dosimeters capable of accurately evaluating the dose distribution of heavy ion beams. In contrast, reduction of t...
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MDPI AG
2021-11-01
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| Series: | Gels |
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| Online Access: | https://www.mdpi.com/2310-2861/7/4/233 |
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| author | Shinya Mizukami Yusuke Watanabe Takahiro Mizoguchi Tsutomu Gomi Hidetake Hara Hideyuki Takei Nobuhisa Fukunishi Kenichi L. Ishikawa Shigekazu Fukuda Takuya Maeyama |
| author_facet | Shinya Mizukami Yusuke Watanabe Takahiro Mizoguchi Tsutomu Gomi Hidetake Hara Hideyuki Takei Nobuhisa Fukunishi Kenichi L. Ishikawa Shigekazu Fukuda Takuya Maeyama |
| author_sort | Shinya Mizukami |
| collection | DOAJ |
| description | MRI-based gel dosimeters are attractive systems for the evaluation of complex dose distributions in radiotherapy. In particular, the nanocomposite Fricke gel dosimeter is one among a few dosimeters capable of accurately evaluating the dose distribution of heavy ion beams. In contrast, reduction of the scanning time is a challenging issue for the acquisition of three-dimensional volume data. In this study, we investigated a three-dimensional dose distribution measurement method for heavy ion beams using variable flip angle (VFA), which is expected to significantly reduce the MRI scanning time. Our findings clarified that the whole three-dimensional dose distribution could be evaluated within the conventional imaging time (20 min) and quality of one cross-section. |
| first_indexed | 2024-03-10T04:03:06Z |
| format | Article |
| id | doaj.art-2d382ab6f2ac42e58ad9f78b0e4b6041 |
| institution | Directory Open Access Journal |
| issn | 2310-2861 |
| language | English |
| last_indexed | 2024-03-10T04:03:06Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gels |
| spelling | doaj.art-2d382ab6f2ac42e58ad9f78b0e4b60412023-11-23T08:28:20ZengMDPI AGGels2310-28612021-11-017423310.3390/gels7040233Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid <i>T</i><sub>1</sub> Mapping MethodShinya Mizukami0Yusuke Watanabe1Takahiro Mizoguchi2Tsutomu Gomi3Hidetake Hara4Hideyuki Takei5Nobuhisa Fukunishi6Kenichi L. Ishikawa7Shigekazu Fukuda8Takuya Maeyama9School of Allied Health Sciences, Kitasato University, Sagamihara 252-0373, JapanSchool of Allied Health Sciences, Kitasato University, Sagamihara 252-0373, JapanGraduate School of Medical Sciences, Kitasato University, Sagamihara 252-0373, JapanSchool of Allied Health Sciences, Kitasato University, Sagamihara 252-0373, JapanSchool of Allied Health Sciences, Kitasato University, Sagamihara 252-0373, JapanProton Medical Research Center, University of Tsukuba Hospital, Tsukuba 305-8576, JapanNishina Center for Accelerator-Based Science, RIKEN, Saitama 351-0198, JapanDepartment of Nuclear Engineering and Management, Graduate School of Engineering, The University of Tokyo, Tokyo 113-8656, JapanQST Hospital, National Institutes for Quantum Science and Technology, Chiba 263-8555, JapanNishina Center for Accelerator-Based Science, RIKEN, Saitama 351-0198, JapanMRI-based gel dosimeters are attractive systems for the evaluation of complex dose distributions in radiotherapy. In particular, the nanocomposite Fricke gel dosimeter is one among a few dosimeters capable of accurately evaluating the dose distribution of heavy ion beams. In contrast, reduction of the scanning time is a challenging issue for the acquisition of three-dimensional volume data. In this study, we investigated a three-dimensional dose distribution measurement method for heavy ion beams using variable flip angle (VFA), which is expected to significantly reduce the MRI scanning time. Our findings clarified that the whole three-dimensional dose distribution could be evaluated within the conventional imaging time (20 min) and quality of one cross-section.https://www.mdpi.com/2310-2861/7/4/233heavy ion beam dosimetrygel dosimeternanocomposite Frickelinear energy transferMRIvariable flip angle |
| spellingShingle | Shinya Mizukami Yusuke Watanabe Takahiro Mizoguchi Tsutomu Gomi Hidetake Hara Hideyuki Takei Nobuhisa Fukunishi Kenichi L. Ishikawa Shigekazu Fukuda Takuya Maeyama Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid <i>T</i><sub>1</sub> Mapping Method Gels heavy ion beam dosimetry gel dosimeter nanocomposite Fricke linear energy transfer MRI variable flip angle |
| title | Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid <i>T</i><sub>1</sub> Mapping Method |
| title_full | Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid <i>T</i><sub>1</sub> Mapping Method |
| title_fullStr | Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid <i>T</i><sub>1</sub> Mapping Method |
| title_full_unstemmed | Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid <i>T</i><sub>1</sub> Mapping Method |
| title_short | Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid <i>T</i><sub>1</sub> Mapping Method |
| title_sort | whole three dimensional dosimetry of carbon ion beams with an mri based nanocomposite fricke gel dosimeter using rapid i t i sub 1 sub mapping method |
| topic | heavy ion beam dosimetry gel dosimeter nanocomposite Fricke linear energy transfer MRI variable flip angle |
| url | https://www.mdpi.com/2310-2861/7/4/233 |
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