Invasive Mixed Fungal Disease after COVID-19: A Series of Seven Cases
Coronavirus disease 2019 (COVID-19) is a recent global pandemic that is caused by the novel severe acute respiratory syndrome coronavirus 2. The patients of COVID-19 are susceptible to a diverse range of secondary infections, fungal being the most common. The increased risk is proposed to be due to...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2023-06-01
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| Series: | Journal of Laboratory Physicians |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1770699 |
| _version_ | 1797796510693326848 |
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| author | Vaishali A. Walke E. Jayashankar T. Karuna Jai Kumar Chourasia Hemlata Panwar Neelkamal Kapoor Vikas Gupta Sarman Singh |
| author_facet | Vaishali A. Walke E. Jayashankar T. Karuna Jai Kumar Chourasia Hemlata Panwar Neelkamal Kapoor Vikas Gupta Sarman Singh |
| author_sort | Vaishali A. Walke |
| collection | DOAJ |
| description | Coronavirus disease 2019 (COVID-19) is a recent global pandemic that is caused by the novel severe acute respiratory syndrome coronavirus 2. The patients of COVID-19 are susceptible to a diverse range of secondary infections, fungal being the most common. The increased risk is proposed to be due to the generous use of steroids for the treatment of COVID-19 infection and the presence of comorbidities, such as diabetes mellitus, hypertension, preexisting lung diseases, and/or old age. Invasive mixed fungal disease is potentially life-threatening to the patients of COVID-19. In the present series of seven cases, the authors intend to discuss the clinicopathological profile and gamut of histopathological findings in invasive mixed fungal infection comprising of Mucor and Aspergillus in treated patients of COVID-19. Six patients had a clinical diagnosis of sinonasal–orbital invasive fungal disease, while there was a case of lung infection. The acquaintance and knowledge about histomorphology of invasive fungi and the multidisciplinary diagnostic approach not only will aid in early and accurate diagnosis but can guide the clinician for necessary surgical intervention and initiation of appropriate antifungal medications in patients of COVID-19. |
| first_indexed | 2024-03-13T03:34:11Z |
| format | Article |
| id | doaj.art-2d39320fa4034ebc8c54830930128e63 |
| institution | Directory Open Access Journal |
| issn | 0974-2727 0974-7826 |
| language | English |
| last_indexed | 2024-03-13T03:34:11Z |
| publishDate | 2023-06-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Journal of Laboratory Physicians |
| spelling | doaj.art-2d39320fa4034ebc8c54830930128e632023-06-23T23:11:59ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Laboratory Physicians0974-27270974-78262023-06-0110.1055/s-0043-1770699Invasive Mixed Fungal Disease after COVID-19: A Series of Seven CasesVaishali A. Walke0E. Jayashankar1T. Karuna2Jai Kumar Chourasia3Hemlata Panwar4Neelkamal Kapoor5Vikas Gupta6Sarman Singh7Path & Lab Medicine, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, IndiaPath & Lab Medicine, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, IndiaMicrobiology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, IndiaPath & Lab Medicine, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, IndiaPath & Lab Medicine, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, IndiaPath & Lab Medicine, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, IndiaOtorhinolaryngology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, IndiaInstitute of Science & Engineering Research Centre, IISER, Bhopal, Madhya Pradesh, IndiaCoronavirus disease 2019 (COVID-19) is a recent global pandemic that is caused by the novel severe acute respiratory syndrome coronavirus 2. The patients of COVID-19 are susceptible to a diverse range of secondary infections, fungal being the most common. The increased risk is proposed to be due to the generous use of steroids for the treatment of COVID-19 infection and the presence of comorbidities, such as diabetes mellitus, hypertension, preexisting lung diseases, and/or old age. Invasive mixed fungal disease is potentially life-threatening to the patients of COVID-19. In the present series of seven cases, the authors intend to discuss the clinicopathological profile and gamut of histopathological findings in invasive mixed fungal infection comprising of Mucor and Aspergillus in treated patients of COVID-19. Six patients had a clinical diagnosis of sinonasal–orbital invasive fungal disease, while there was a case of lung infection. The acquaintance and knowledge about histomorphology of invasive fungi and the multidisciplinary diagnostic approach not only will aid in early and accurate diagnosis but can guide the clinician for necessary surgical intervention and initiation of appropriate antifungal medications in patients of COVID-19.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1770699mixed fungal infectionaspergillosismucormycosiscovid-19. |
| spellingShingle | Vaishali A. Walke E. Jayashankar T. Karuna Jai Kumar Chourasia Hemlata Panwar Neelkamal Kapoor Vikas Gupta Sarman Singh Invasive Mixed Fungal Disease after COVID-19: A Series of Seven Cases Journal of Laboratory Physicians mixed fungal infection aspergillosis mucormycosis covid-19. |
| title | Invasive Mixed Fungal Disease after COVID-19: A Series of Seven Cases |
| title_full | Invasive Mixed Fungal Disease after COVID-19: A Series of Seven Cases |
| title_fullStr | Invasive Mixed Fungal Disease after COVID-19: A Series of Seven Cases |
| title_full_unstemmed | Invasive Mixed Fungal Disease after COVID-19: A Series of Seven Cases |
| title_short | Invasive Mixed Fungal Disease after COVID-19: A Series of Seven Cases |
| title_sort | invasive mixed fungal disease after covid 19 a series of seven cases |
| topic | mixed fungal infection aspergillosis mucormycosis covid-19. |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1770699 |
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