Cerebrovascular function in tension-type headache and migraine with or without aura: Transcranial Doppler study
Abstract The aim of the current study was to determine whether tension-type headache (TTH) and migraine with or without aura have altered anterior and posterior circulation compared with normal volunteers as assessed by Transcranial Doppler (TCD) ultrasonography. The study included 24 patients with...
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Nature Portfolio
2022-08-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-18359-6 |
| _version_ | 1811340407671357440 |
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| author | Eman M. Khedr Mohammed A. Abbas Ayman Gamea Mohamed A. Sadek Ahmed F. Zaki |
| author_facet | Eman M. Khedr Mohammed A. Abbas Ayman Gamea Mohamed A. Sadek Ahmed F. Zaki |
| author_sort | Eman M. Khedr |
| collection | DOAJ |
| description | Abstract The aim of the current study was to determine whether tension-type headache (TTH) and migraine with or without aura have altered anterior and posterior circulation compared with normal volunteers as assessed by Transcranial Doppler (TCD) ultrasonography. The study included 24 patients with chronic TTH and 37 patients with migraine (16 with aura and 21 without aura) classified according to the diagnostic criteria of the International Headache Society 2018. They were compared with a control group of 50 age- and sex-matched healthy volunteers. Each participant was examined with TCD ultrasonography of the middle, anterior and posterior cerebral and vertebral arteries (MCA, ACA, PCA, and VA) at rest. Patients in the TTH group had a significantly lower peak systolic velocity (PSV) and mean flow velocity (MFV) in the MCA compared with controls, whereas EDV and MFV in the ACA were significantly higher in the migraine without aura group than controls. Within the 3 groups of patients, the TTH group had significantly lower PSV in the MCA and PCA than the group of migraine with aura. In addition, the TTH group had significantly lower PSV and MFV in the MCA and a lower EDV in the VA than migraine patients without aura. In conclusion, the possibility of cerebrovascular changes is confirmed in the present study in both TTH and migraine without aura. The former has a low MFV in the MCA whereas the latter has a high MFV in the ACA. |
| first_indexed | 2024-04-13T18:40:33Z |
| format | Article |
| id | doaj.art-2d3c513dc5de45bd9d08204f46795f39 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-13T18:40:33Z |
| publishDate | 2022-08-01 |
| publisher | Nature Portfolio |
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| series | Scientific Reports |
| spelling | doaj.art-2d3c513dc5de45bd9d08204f46795f392022-12-22T02:34:43ZengNature PortfolioScientific Reports2045-23222022-08-011211710.1038/s41598-022-18359-6Cerebrovascular function in tension-type headache and migraine with or without aura: Transcranial Doppler studyEman M. Khedr0Mohammed A. Abbas1Ayman Gamea2Mohamed A. Sadek3Ahmed F. Zaki4Department of Neuropsychiatry, Faculty of Medicine, Assiut University HospitalNeuropsychiatry Department, Faculty of Medicine, Luxor UniversityNeuropsychiatric Department, Faculty of Medicine, South Valley University, Qena University HospitalNeuropsychiatric Department, Faculty of Medicine, South Valley University, Qena University HospitalNeuropsychiatric Department, Faculty of Medicine, South Valley University, Qena University HospitalAbstract The aim of the current study was to determine whether tension-type headache (TTH) and migraine with or without aura have altered anterior and posterior circulation compared with normal volunteers as assessed by Transcranial Doppler (TCD) ultrasonography. The study included 24 patients with chronic TTH and 37 patients with migraine (16 with aura and 21 without aura) classified according to the diagnostic criteria of the International Headache Society 2018. They were compared with a control group of 50 age- and sex-matched healthy volunteers. Each participant was examined with TCD ultrasonography of the middle, anterior and posterior cerebral and vertebral arteries (MCA, ACA, PCA, and VA) at rest. Patients in the TTH group had a significantly lower peak systolic velocity (PSV) and mean flow velocity (MFV) in the MCA compared with controls, whereas EDV and MFV in the ACA were significantly higher in the migraine without aura group than controls. Within the 3 groups of patients, the TTH group had significantly lower PSV in the MCA and PCA than the group of migraine with aura. In addition, the TTH group had significantly lower PSV and MFV in the MCA and a lower EDV in the VA than migraine patients without aura. In conclusion, the possibility of cerebrovascular changes is confirmed in the present study in both TTH and migraine without aura. The former has a low MFV in the MCA whereas the latter has a high MFV in the ACA.https://doi.org/10.1038/s41598-022-18359-6 |
| spellingShingle | Eman M. Khedr Mohammed A. Abbas Ayman Gamea Mohamed A. Sadek Ahmed F. Zaki Cerebrovascular function in tension-type headache and migraine with or without aura: Transcranial Doppler study Scientific Reports |
| title | Cerebrovascular function in tension-type headache and migraine with or without aura: Transcranial Doppler study |
| title_full | Cerebrovascular function in tension-type headache and migraine with or without aura: Transcranial Doppler study |
| title_fullStr | Cerebrovascular function in tension-type headache and migraine with or without aura: Transcranial Doppler study |
| title_full_unstemmed | Cerebrovascular function in tension-type headache and migraine with or without aura: Transcranial Doppler study |
| title_short | Cerebrovascular function in tension-type headache and migraine with or without aura: Transcranial Doppler study |
| title_sort | cerebrovascular function in tension type headache and migraine with or without aura transcranial doppler study |
| url | https://doi.org/10.1038/s41598-022-18359-6 |
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