Investigation of protective effects of olanzapine on impaired learning and memory using behavioral tests in a rat model of Alzheimer’s disease

Investigation of protective effects of olanzapine on impaired learning and memory using behavioral tests in a rat model of Alzheimer’s disease

IntroductionEvidence suggests that oxidative stress plays a critical role in the pathogenesis and progression of Alzheimer’s disease (AD). Consequently, antioxidants may mitigate neurotoxicity induced by beta-amyloid (Aβ) and potentially reduce cell death. Previous research has demonstrated that ola...

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Hlavní autoři: Somayeh Komaki, Parsa Amiri, Samaneh Safari, Ebrahim Abbasi, Fatemeh Ramezani-Aliakbari, Mandana Golipoor, Masoumeh Kourosh-Arami, Masome Rashno, Alireza Komaki
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2025-02-01
Edice:Frontiers in Aging Neuroscience
Témata:
Alzheimer’s disease
Aβ
olanzapine
cognition
anxiety-like behavior
rat
On-line přístup:https://www.frontiersin.org/articles/10.3389/fnagi.2025.1376074/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2025.1376074/full

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