The Combination of Metformin and Disulfiram-Cu for Effective Radiosensitization on Glioblastoma Cells

The Combination of Metformin and Disulfiram-Cu for Effective Radiosensitization on Glioblastoma Cells

Objective: Glioblastoma (GBM) is one of the devastating types of primary brain tumors with a negligible response to standard therapy. Repurposing drugs, such as disulfiram (DSF) and metformin (Met) have shown antitumor properties in different cell lines, including GBM. In the present study, we foc...

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Bibliographic Details
Main Authors: Narges Rezaei, Ali Neshasteh-Riz, Zohreh Mazaheri, Fereshteh Koosha, Mahmood Hoormand
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2020-10-01
Series:Cell Journal
Subjects:
apoptosis
disulfiram
glioblastoma
irradiation
metformin
Online Access:https://celljournal.org/journal/article/abstract/6798

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