Massive bleeding from a duodenal ulcer in a child with influenza infection: A case report of endoscopic findings
Abstract Gastrointestinal bleeding or perforation following influenza infection is rare. We encountered a pediatric case of hemorrhagic duodenal ulcer following influenza A infection. The patient was a 1‐year and 4‐month‐old boy who was diagnosed with influenza A infection and treated with laninamiv...
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| Format: | Article |
| Language: | English |
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Wiley
2023-04-01
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| Series: | DEN Open |
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| Online Access: | https://doi.org/10.1002/deo2.155 |
| _version_ | 1797837217650966528 |
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| author | Kenta Ishimoto Koichiro Yoshimaru Yasuyuki Uchida Keisuke Kajihara Satoshi Obata Toshiharu Matsuura Tatsuro Tajiri |
| author_facet | Kenta Ishimoto Koichiro Yoshimaru Yasuyuki Uchida Keisuke Kajihara Satoshi Obata Toshiharu Matsuura Tatsuro Tajiri |
| author_sort | Kenta Ishimoto |
| collection | DOAJ |
| description | Abstract Gastrointestinal bleeding or perforation following influenza infection is rare. We encountered a pediatric case of hemorrhagic duodenal ulcer following influenza A infection. The patient was a 1‐year and 4‐month‐old boy who was diagnosed with influenza A infection and treated with laninamivir octanoate. After inhalation, he had diarrhea, poor appetite, and melena. The next day, he had hematochezia and developed hemorrhagic shock. Contrast‐enhanced computed tomography showed extravasation in the descending part of the duodenum. Esophagogastroduodenoscopy revealed spurting bleeding from a Dieulafoy's lesion on the oral side of the major papilla, and he underwent hemostasis by clipping. From the bulb to the descending part of the duodenum, the mucosa appeared atrophic with spotty redness on the circular folds and multiple and irregularly shaped erosions. Almost all mucosal lesions had healed by the eighth day, and he was monitored as an outpatient for more than one year without re‐bleeding. Intestinal ischemia, viral invasion, and drug reaction of laninamivir octanoate may be involved in duodenal mucosal injury. Acute duodenal ulcers may occur in children with influenza infection, especially young children. |
| first_indexed | 2024-04-09T15:22:17Z |
| format | Article |
| id | doaj.art-2d3ea2322b3143b7883c7dc5482ac655 |
| institution | Directory Open Access Journal |
| issn | 2692-4609 |
| language | English |
| last_indexed | 2024-04-09T15:22:17Z |
| publishDate | 2023-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | DEN Open |
| spelling | doaj.art-2d3ea2322b3143b7883c7dc5482ac6552023-04-29T05:12:58ZengWileyDEN Open2692-46092023-04-0131n/an/a10.1002/deo2.155Massive bleeding from a duodenal ulcer in a child with influenza infection: A case report of endoscopic findingsKenta Ishimoto0Koichiro Yoshimaru1Yasuyuki Uchida2Keisuke Kajihara3Satoshi Obata4Toshiharu Matsuura5Tatsuro Tajiri6Department of Pediatric Surgery, Reproductive and Developmental Medicine, Faculty of Medical Sciences Kyushu University Fukuoka JapanDepartment of Pediatric Surgery, Reproductive and Developmental Medicine, Faculty of Medical Sciences Kyushu University Fukuoka JapanDepartment of Pediatric Surgery, Reproductive and Developmental Medicine, Faculty of Medical Sciences Kyushu University Fukuoka JapanDepartment of Pediatric Surgery, Reproductive and Developmental Medicine, Faculty of Medical Sciences Kyushu University Fukuoka JapanDepartment of Pediatric Surgery, Reproductive and Developmental Medicine, Faculty of Medical Sciences Kyushu University Fukuoka JapanDepartment of Pediatric Surgery, Reproductive and Developmental Medicine, Faculty of Medical Sciences Kyushu University Fukuoka JapanDepartment of Pediatric Surgery, Reproductive and Developmental Medicine, Faculty of Medical Sciences Kyushu University Fukuoka JapanAbstract Gastrointestinal bleeding or perforation following influenza infection is rare. We encountered a pediatric case of hemorrhagic duodenal ulcer following influenza A infection. The patient was a 1‐year and 4‐month‐old boy who was diagnosed with influenza A infection and treated with laninamivir octanoate. After inhalation, he had diarrhea, poor appetite, and melena. The next day, he had hematochezia and developed hemorrhagic shock. Contrast‐enhanced computed tomography showed extravasation in the descending part of the duodenum. Esophagogastroduodenoscopy revealed spurting bleeding from a Dieulafoy's lesion on the oral side of the major papilla, and he underwent hemostasis by clipping. From the bulb to the descending part of the duodenum, the mucosa appeared atrophic with spotty redness on the circular folds and multiple and irregularly shaped erosions. Almost all mucosal lesions had healed by the eighth day, and he was monitored as an outpatient for more than one year without re‐bleeding. Intestinal ischemia, viral invasion, and drug reaction of laninamivir octanoate may be involved in duodenal mucosal injury. Acute duodenal ulcers may occur in children with influenza infection, especially young children.https://doi.org/10.1002/deo2.155childrenduodenal ulcerhemorrhaginginfluenzalaninamivir octanoate |
| spellingShingle | Kenta Ishimoto Koichiro Yoshimaru Yasuyuki Uchida Keisuke Kajihara Satoshi Obata Toshiharu Matsuura Tatsuro Tajiri Massive bleeding from a duodenal ulcer in a child with influenza infection: A case report of endoscopic findings DEN Open children duodenal ulcer hemorrhaging influenza laninamivir octanoate |
| title | Massive bleeding from a duodenal ulcer in a child with influenza infection: A case report of endoscopic findings |
| title_full | Massive bleeding from a duodenal ulcer in a child with influenza infection: A case report of endoscopic findings |
| title_fullStr | Massive bleeding from a duodenal ulcer in a child with influenza infection: A case report of endoscopic findings |
| title_full_unstemmed | Massive bleeding from a duodenal ulcer in a child with influenza infection: A case report of endoscopic findings |
| title_short | Massive bleeding from a duodenal ulcer in a child with influenza infection: A case report of endoscopic findings |
| title_sort | massive bleeding from a duodenal ulcer in a child with influenza infection a case report of endoscopic findings |
| topic | children duodenal ulcer hemorrhaging influenza laninamivir octanoate |
| url | https://doi.org/10.1002/deo2.155 |
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