Application of prothrombin complex concentrate for reversal of direct oral anticoagulants in clinical practice: indications, patient characteristics and clinical outcomes compared to reversal of vitamin K antagonists

Application of prothrombin complex concentrate for reversal of direct oral anticoagulants in clinical practice: indications, patient characteristics and clinical outcomes compared to reversal of vitamin K antagonists

Abstract Background Prothrombin complex concentrate (PCC) is widely used to reverse the action of direct oral anticoagulants (DOACs) in accordance with current guidelines and because of a lack of specific reversal agents. Indications, clinical characteristics and patient outcomes of patients might d...

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Bibliographic Details
Main Authors: Martin Müller, Jonathan Eastline, Michael Nagler, Aristomenis K. Exadaktylos, Thomas C. Sauter
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Subjects:
Anticoagulants
Antidote
Bleeding
Direct oral anticoagulants
Vitamin K antagonist
Online Access:http://link.springer.com/article/10.1186/s13049-019-0625-3

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http://link.springer.com/article/10.1186/s13049-019-0625-3

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