Non-canonical Glucocorticoid Receptor Transactivation of gilz by Alcohol Suppresses Cell Inflammatory Response

Non-canonical Glucocorticoid Receptor Transactivation of gilz by Alcohol Suppresses Cell Inflammatory Response

Acute alcohol exposure suppresses cell inflammatory response. The underlying mechanism has not been fully defined. Here we report that alcohol was able to activate glucocorticoid receptor (GR) signaling in the absence of glucocorticoids (GCs) and upregulated glucocorticoid-induced leucine zipper (gi...

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Bibliographic Details
Main Authors:	Hang Pong Ng, Scott Jennings, Jack Wang, Patricia E. Molina, Steve Nelson, Guoshun Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-06-01
Series:	Frontiers in Immunology
Subjects:	glucocorticoid receptor glucocorticoid-induced leucine zipper glucocorticoid alcohol LPS inflammatory response
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.00661/full

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