A Non-Nutritive Feeding Intervention Alters the Expression of Efflux Transporters in the Gastrointestinal Tract

A Non-Nutritive Feeding Intervention Alters the Expression of Efflux Transporters in the Gastrointestinal Tract

Intestinal interactions with nutrients, xenobiotics and endogenous hormones can influence the expression of clinically relevant membrane transporters. These changes in the gastrointestinal (GI) physiology can in turn affect the absorption of numerous drug substrates. Several studies have examined th...

Full description

Bibliographic Details
Main Authors: Yang Mai, Francesca K. H. Gavins, Liu Dou, Jing Liu, Farhan Taherali, Manal E. Alkahtani, Sudaxshina Murdan, Abdul W. Basit, Mine Orlu
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Pharmaceutics
Subjects:
food effect
sex differences
hormones
efflux pumps
preclinical drug development
oral delivery
Online Access:https://www.mdpi.com/1999-4923/13/11/1789

Internet

https://www.mdpi.com/1999-4923/13/11/1789

Similar Items