Reticular materials as chiral stationary phases in chromatography
Metal-organic frameworks (MOFs) and covalent organic frameworks (COFs) are reticular materials with outstanding physical and chemical properties. Among these properties, their impressive surface area, highly uniform porosity, adequate synthetic versatility, and stability, have undoubtedly contribute...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-11-01
|
| Series: | Journal of Chromatography Open |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772391721000025 |
| _version_ | 1819097244507308032 |
|---|---|
| author | Iván Taima-Mancera Verónica Pino |
| author_facet | Iván Taima-Mancera Verónica Pino |
| author_sort | Iván Taima-Mancera |
| collection | DOAJ |
| description | Metal-organic frameworks (MOFs) and covalent organic frameworks (COFs) are reticular materials with outstanding physical and chemical properties. Among these properties, their impressive surface area, highly uniform porosity, adequate synthetic versatility, and stability, have undoubtedly contributed to their success in a wide variety of analytical applications. One of the most recent and interesting applications of MOFs and COFs lies in the chromatographic field, in which they have been incorporated as stationary phases, showing particular success when involved in the resolution of racemic mixtures. For this purpose, a chiral structural component (which is frequently an organic linker) needs to be incorporated in the material to permit its use as chiral stationary phase (CSP). This review attempts to cover a historic overview on the use of MOFs and COFs as CSPs in chromatography, while describing the main applications reported and discussing the synthetic issues of these CSPs, main column configurations, and the analytical performance of the CSPs obtained.Image, graphical abstract |
| first_indexed | 2024-12-22T00:12:01Z |
| format | Article |
| id | doaj.art-2d4bd627e6cb4571a56c759255348ae0 |
| institution | Directory Open Access Journal |
| issn | 2772-3917 |
| language | English |
| last_indexed | 2024-12-22T00:12:01Z |
| publishDate | 2021-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Chromatography Open |
| spelling | doaj.art-2d4bd627e6cb4571a56c759255348ae02022-12-21T18:45:25ZengElsevierJournal of Chromatography Open2772-39172021-11-011100002Reticular materials as chiral stationary phases in chromatographyIván Taima-Mancera0Verónica Pino1Departamento de Química, Unidad Departamental de Química Analítica, Universidad de La Laguna (ULL), La Laguna, Tenerife, 38206, SpainDepartamento de Química, Unidad Departamental de Química Analítica, Universidad de La Laguna (ULL), La Laguna, Tenerife, 38206, Spain; Unidad de Investigación de Bioanalítica y Medioambiente, Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Universidad de La Laguna (ULL), La Laguna, Tenerife, 38206, Spain; Corresponding authorMetal-organic frameworks (MOFs) and covalent organic frameworks (COFs) are reticular materials with outstanding physical and chemical properties. Among these properties, their impressive surface area, highly uniform porosity, adequate synthetic versatility, and stability, have undoubtedly contributed to their success in a wide variety of analytical applications. One of the most recent and interesting applications of MOFs and COFs lies in the chromatographic field, in which they have been incorporated as stationary phases, showing particular success when involved in the resolution of racemic mixtures. For this purpose, a chiral structural component (which is frequently an organic linker) needs to be incorporated in the material to permit its use as chiral stationary phase (CSP). This review attempts to cover a historic overview on the use of MOFs and COFs as CSPs in chromatography, while describing the main applications reported and discussing the synthetic issues of these CSPs, main column configurations, and the analytical performance of the CSPs obtained.Image, graphical abstracthttp://www.sciencedirect.com/science/article/pii/S2772391721000025ChiralityChiral stationary phasesChromatographyReticular materialsMetal-organic frameworksCovalent organic frameworks |
| spellingShingle | Iván Taima-Mancera Verónica Pino Reticular materials as chiral stationary phases in chromatography Journal of Chromatography Open Chirality Chiral stationary phases Chromatography Reticular materials Metal-organic frameworks Covalent organic frameworks |
| title | Reticular materials as chiral stationary phases in chromatography |
| title_full | Reticular materials as chiral stationary phases in chromatography |
| title_fullStr | Reticular materials as chiral stationary phases in chromatography |
| title_full_unstemmed | Reticular materials as chiral stationary phases in chromatography |
| title_short | Reticular materials as chiral stationary phases in chromatography |
| title_sort | reticular materials as chiral stationary phases in chromatography |
| topic | Chirality Chiral stationary phases Chromatography Reticular materials Metal-organic frameworks Covalent organic frameworks |
| url | http://www.sciencedirect.com/science/article/pii/S2772391721000025 |
| work_keys_str_mv | AT ivantaimamancera reticularmaterialsaschiralstationaryphasesinchromatography AT veronicapino reticularmaterialsaschiralstationaryphasesinchromatography |