Dynamics of Emergency Cardiovascular Hospital Admissions and In-Hospital Mortality During the COVID-19 Pandemic: Time Series Analysis and Impact of Socioeconomic Factors
AimsThis study aimed to evaluate the decline in urgent cardiovascular hospital admissions and in-hospital mortality during the COVID pandemic in two successive waves, and to evaluate differences by sex, age, and deprivation index subgroups.Methods and ResultsWe obtained acute cardiovascular hospital...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-04-01
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| Series: | Frontiers in Cardiovascular Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.827212/full |
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| author | Claudia Álvarez-Martín Claudia Álvarez-Martín Aida Ribera Aida Ribera Aida Ribera Josep Ramon Marsal Josep Ramon Marsal Albert Ariza-Solé Albert Ariza-Solé Albert Ariza-Solé Santiago Pérez-Hoyos Santiago Pérez-Hoyos Gerard Oristrell Gerard Oristrell Toni Soriano-Colomé Rafael Romaguera Rafael Romaguera Jose Ignacio Pijoan Jose Ignacio Pijoan Rosa M. Lidón Rosa M. Lidón Josepa Mauri Josepa Mauri Ignacio Ferreira-González Ignacio Ferreira-González Ignacio Ferreira-González |
| author_facet | Claudia Álvarez-Martín Claudia Álvarez-Martín Aida Ribera Aida Ribera Aida Ribera Josep Ramon Marsal Josep Ramon Marsal Albert Ariza-Solé Albert Ariza-Solé Albert Ariza-Solé Santiago Pérez-Hoyos Santiago Pérez-Hoyos Gerard Oristrell Gerard Oristrell Toni Soriano-Colomé Rafael Romaguera Rafael Romaguera Jose Ignacio Pijoan Jose Ignacio Pijoan Rosa M. Lidón Rosa M. Lidón Josepa Mauri Josepa Mauri Ignacio Ferreira-González Ignacio Ferreira-González Ignacio Ferreira-González |
| author_sort | Claudia Álvarez-Martín |
| collection | DOAJ |
| description | AimsThis study aimed to evaluate the decline in urgent cardiovascular hospital admissions and in-hospital mortality during the COVID pandemic in two successive waves, and to evaluate differences by sex, age, and deprivation index subgroups.Methods and ResultsWe obtained acute cardiovascular hospital episodes during the years 2019–2020 from region-wide data on public healthcare usage for the population of Catalonia (North-East Spain). We fitted time models to estimate the incidence rate ratios (IRRs) of the acute coronary syndrome (ACS) and acute heart failure (HF) admissions during the first pandemic wave, the between-waves period, and the second wave compared with the corresponding pre-COVID-19 periods and to test for the interaction with sex, age, and area-based socioeconomic level. We evaluated the effect of COVID-19 period on in-hospital mortality. ACS (n = 8,636) and HF (n = 27,566) episodes were defined using primary diagnostic ICD-10 codes. ACS and HF admissions decreased during the first wave (IRR = 0.66, 95%CI: 0.58–0.76 and IRR = 0.61, 95% CI: 0.55–0.68, respectively) and during the second wave (IRR = 0.80, 95%CI: 0.72–0.88 and IRR = 0.76, 95%CI: 0.69–0.84, respectively); acute HF admissions also decreased in the period between waves (IRR: 0.81, 95%CI: 0.74–0.89). The impact was similar in all sex and socioeconomic subgroups and was higher in older patients with ACS. In-hospital mortality was higher than expected only during the first wave.ConclusionDuring the first wave of the COVID-19 pandemic, there was a marked decline in urgent cardiovascular hospital admissions that were attenuated during the second wave. Both the decline and the attenuation of the effect have been similar in all subgroups regardless of age, sex, or socioeconomic status. In-hospital mortality for ACS and HF episodes increased during the first wave, but not during the second wave. |
| first_indexed | 2024-04-12T13:09:03Z |
| format | Article |
| id | doaj.art-2d5009aaeebe42b898cdf811337db3ec |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-12T13:09:03Z |
| publishDate | 2022-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-2d5009aaeebe42b898cdf811337db3ec2022-12-22T03:31:55ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2022-04-01910.3389/fcvm.2022.827212827212Dynamics of Emergency Cardiovascular Hospital Admissions and In-Hospital Mortality During the COVID-19 Pandemic: Time Series Analysis and Impact of Socioeconomic FactorsClaudia Álvarez-Martín0Claudia Álvarez-Martín1Aida Ribera2Aida Ribera3Aida Ribera4Josep Ramon Marsal5Josep Ramon Marsal6Albert Ariza-Solé7Albert Ariza-Solé8Albert Ariza-Solé9Santiago Pérez-Hoyos10Santiago Pérez-Hoyos11Gerard Oristrell12Gerard Oristrell13Toni Soriano-Colomé14Rafael Romaguera15Rafael Romaguera16Jose Ignacio Pijoan17Jose Ignacio Pijoan18Rosa M. Lidón19Rosa M. Lidón20Josepa Mauri21Josepa Mauri22Ignacio Ferreira-González23Ignacio Ferreira-González24Ignacio Ferreira-González25Cardiovascular Research and Epidemiology Unit, Cardiology Department, University Hospital Vall d’Hebron and Vall d’Hebron Research Institute, Barcelona, SpainCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, SpainCardiovascular Research and Epidemiology Unit, Cardiology Department, University Hospital Vall d’Hebron and Vall d’Hebron Research Institute, Barcelona, SpainCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, SpainRecerca en Envelliment, Fragilitat i Transicions (REFiT) Barcelona Research Group, Parc Sanitari Pere Virgili and Vall d’Hebron Institute of Research, Barcelona, SpainCardiovascular Research and Epidemiology Unit, Cardiology Department, University Hospital Vall d’Hebron and Vall d’Hebron Research Institute, Barcelona, SpainCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, SpainCardiology Department, Hospital Universitari de Bellvitge, Barcelona, SpainBioheart, Grup de Malalties Cardiovasculars, Institut d’Investigació Biomèdica de Bellvitge (IDIBELL), L’Hospitalet de Llobregat, Barcelona, SpainCentro de Investigación Biomédica en Red en Enfermedades Cardiovasculares (CIBERCV), Madrid, SpainStatistics and Bioinformatics Unit, Vall d’Hebron Research Institute, Barcelona, SpainStatistics Department, Faculty of Biology, University of Barcelona, Barcelona, SpainCentro de Investigación Biomédica en Red en Enfermedades Cardiovasculares (CIBERCV), Madrid, SpainCardiology Department, University Hospital Vall d’Hebron, Universitat Autònoma de Barcelona, Barcelona, SpainCardiology Department, University Hospital Vall d’Hebron, Universitat Autònoma de Barcelona, Barcelona, SpainCardiology Department, Hospital Universitari de Bellvitge, Barcelona, SpainBioheart, Grup de Malalties Cardiovasculars, Institut d’Investigació Biomèdica de Bellvitge (IDIBELL), L’Hospitalet de Llobregat, Barcelona, SpainCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain0Clinical Epidemiology Unit, Hospital Universitario Cruces/BioCruces-Bizkaia Health Research Institute, Barakaldo, SpainCentro de Investigación Biomédica en Red en Enfermedades Cardiovasculares (CIBERCV), Madrid, SpainCardiology Department, University Hospital Vall d’Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain1Cardiology Department, Hospital German Trias i Pujol, Barcelona, Spain2Director Plan for Cardiovascular Diseases, Pla Director de Malalties Cardiovasculars (PDMCV), Department of Health, Catalan Government, Barcelona, SpainCardiovascular Research and Epidemiology Unit, Cardiology Department, University Hospital Vall d’Hebron and Vall d’Hebron Research Institute, Barcelona, SpainCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, SpainCardiology Department, University Hospital Vall d’Hebron, Universitat Autònoma de Barcelona, Barcelona, SpainAimsThis study aimed to evaluate the decline in urgent cardiovascular hospital admissions and in-hospital mortality during the COVID pandemic in two successive waves, and to evaluate differences by sex, age, and deprivation index subgroups.Methods and ResultsWe obtained acute cardiovascular hospital episodes during the years 2019–2020 from region-wide data on public healthcare usage for the population of Catalonia (North-East Spain). We fitted time models to estimate the incidence rate ratios (IRRs) of the acute coronary syndrome (ACS) and acute heart failure (HF) admissions during the first pandemic wave, the between-waves period, and the second wave compared with the corresponding pre-COVID-19 periods and to test for the interaction with sex, age, and area-based socioeconomic level. We evaluated the effect of COVID-19 period on in-hospital mortality. ACS (n = 8,636) and HF (n = 27,566) episodes were defined using primary diagnostic ICD-10 codes. ACS and HF admissions decreased during the first wave (IRR = 0.66, 95%CI: 0.58–0.76 and IRR = 0.61, 95% CI: 0.55–0.68, respectively) and during the second wave (IRR = 0.80, 95%CI: 0.72–0.88 and IRR = 0.76, 95%CI: 0.69–0.84, respectively); acute HF admissions also decreased in the period between waves (IRR: 0.81, 95%CI: 0.74–0.89). The impact was similar in all sex and socioeconomic subgroups and was higher in older patients with ACS. In-hospital mortality was higher than expected only during the first wave.ConclusionDuring the first wave of the COVID-19 pandemic, there was a marked decline in urgent cardiovascular hospital admissions that were attenuated during the second wave. Both the decline and the attenuation of the effect have been similar in all subgroups regardless of age, sex, or socioeconomic status. In-hospital mortality for ACS and HF episodes increased during the first wave, but not during the second wave.https://www.frontiersin.org/articles/10.3389/fcvm.2022.827212/fullCOVID-19acute coronary syndromemyocardial infarctionheart failuretime-series |
| spellingShingle | Claudia Álvarez-Martín Claudia Álvarez-Martín Aida Ribera Aida Ribera Aida Ribera Josep Ramon Marsal Josep Ramon Marsal Albert Ariza-Solé Albert Ariza-Solé Albert Ariza-Solé Santiago Pérez-Hoyos Santiago Pérez-Hoyos Gerard Oristrell Gerard Oristrell Toni Soriano-Colomé Rafael Romaguera Rafael Romaguera Jose Ignacio Pijoan Jose Ignacio Pijoan Rosa M. Lidón Rosa M. Lidón Josepa Mauri Josepa Mauri Ignacio Ferreira-González Ignacio Ferreira-González Ignacio Ferreira-González Dynamics of Emergency Cardiovascular Hospital Admissions and In-Hospital Mortality During the COVID-19 Pandemic: Time Series Analysis and Impact of Socioeconomic Factors Frontiers in Cardiovascular Medicine COVID-19 acute coronary syndrome myocardial infarction heart failure time-series |
| title | Dynamics of Emergency Cardiovascular Hospital Admissions and In-Hospital Mortality During the COVID-19 Pandemic: Time Series Analysis and Impact of Socioeconomic Factors |
| title_full | Dynamics of Emergency Cardiovascular Hospital Admissions and In-Hospital Mortality During the COVID-19 Pandemic: Time Series Analysis and Impact of Socioeconomic Factors |
| title_fullStr | Dynamics of Emergency Cardiovascular Hospital Admissions and In-Hospital Mortality During the COVID-19 Pandemic: Time Series Analysis and Impact of Socioeconomic Factors |
| title_full_unstemmed | Dynamics of Emergency Cardiovascular Hospital Admissions and In-Hospital Mortality During the COVID-19 Pandemic: Time Series Analysis and Impact of Socioeconomic Factors |
| title_short | Dynamics of Emergency Cardiovascular Hospital Admissions and In-Hospital Mortality During the COVID-19 Pandemic: Time Series Analysis and Impact of Socioeconomic Factors |
| title_sort | dynamics of emergency cardiovascular hospital admissions and in hospital mortality during the covid 19 pandemic time series analysis and impact of socioeconomic factors |
| topic | COVID-19 acute coronary syndrome myocardial infarction heart failure time-series |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2022.827212/full |
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