How Safe is Blood? A 5 Year Retrospective Study
Introduction: Blood is a scarce and life saving resource, however blood transfusion can be a source for transmitting life threatening infections if screening is not carried out properly. Aim: The objective of the present study was to assess the prevalence and trend of transfusion transmitted in...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Pvt. Ltd.
2014-03-01
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| Series: | National Journal of Laboratory Medicine |
| Subjects: | |
| Online Access: | http://www.njlm.net/articles/PDF/2000/7645_E(_)_F(H)_Reformatted_PF1(PrH)_PFA(KH)_OLF.pdf |
| _version_ | 1818153472112984064 |
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| author | Apra Kalra Parminder Kaur Gill Gopal Dutt Uniya |
| author_facet | Apra Kalra Parminder Kaur Gill Gopal Dutt Uniya |
| author_sort | Apra Kalra |
| collection | DOAJ |
| description | Introduction: Blood is a scarce and life saving resource,
however blood transfusion can be a source for transmitting
life threatening infections if screening is not carried out
properly.
Aim: The objective of the present study was to assess the
prevalence and trend of transfusion transmitted infections
(HIV, HBsAg, HCV and syphilis and malaria infections in the
pretransfusion blood) among voluntary and replacement
donors in the Department of transfusion Medicine in a
multispecialty hospital of Mohali during the period from Jan
2008 to Dec 2012.
Methods: A retrospective review of donors’ record covering
the period from 2008 to 2012 was carried out. All samples
were screened for HIV, HBsAg, HCV, Syphilis and Malaria.
Results: Of the 45,337 samples studied, 4144 (9.1%)
were voluntary donors and the remaining 41193 (90.8%)
were replacement donors. The overall prevalence of HIV,
HbsAg, HCV and syphilis were 0.44, 1.27, 0.23 and 0.28%,
respectively. One blood donor tested revealed positivity for
malarial parasite. Majority were replacement donors with
male preponderance. In all the markers tested there was
increased prevalence of TTI among the replacement donors
as compared to voluntary donors.
Conclusion: By implementing strict donor criteria and using
sensitive screening tests, it may be possible to reduce the
incidence of TTI in the Indian scenario. |
| first_indexed | 2024-12-11T14:11:09Z |
| format | Article |
| id | doaj.art-2d515890b78042958a40fd031fad8466 |
| institution | Directory Open Access Journal |
| issn | 2277-8551 2455-6882 |
| language | English |
| last_indexed | 2024-12-11T14:11:09Z |
| publishDate | 2014-03-01 |
| publisher | JCDR Research and Publications Pvt. Ltd. |
| record_format | Article |
| series | National Journal of Laboratory Medicine |
| spelling | doaj.art-2d515890b78042958a40fd031fad84662022-12-22T01:03:26ZengJCDR Research and Publications Pvt. Ltd.National Journal of Laboratory Medicine2277-85512455-68822014-03-01311310.7860/NJLM/2014/7645:2000How Safe is Blood? A 5 Year Retrospective StudyApra Kalra0 Parminder Kaur Gill1Gopal Dutt Uniya2Consultant, Fortis Hospital, Mohali, Punjab, India.Senior Resident, Fortis Hospital, Mohali, Punjab, India.Team leader, Fortis Hospital, Mohali, Punjab, India.Introduction: Blood is a scarce and life saving resource, however blood transfusion can be a source for transmitting life threatening infections if screening is not carried out properly. Aim: The objective of the present study was to assess the prevalence and trend of transfusion transmitted infections (HIV, HBsAg, HCV and syphilis and malaria infections in the pretransfusion blood) among voluntary and replacement donors in the Department of transfusion Medicine in a multispecialty hospital of Mohali during the period from Jan 2008 to Dec 2012. Methods: A retrospective review of donors’ record covering the period from 2008 to 2012 was carried out. All samples were screened for HIV, HBsAg, HCV, Syphilis and Malaria. Results: Of the 45,337 samples studied, 4144 (9.1%) were voluntary donors and the remaining 41193 (90.8%) were replacement donors. The overall prevalence of HIV, HbsAg, HCV and syphilis were 0.44, 1.27, 0.23 and 0.28%, respectively. One blood donor tested revealed positivity for malarial parasite. Majority were replacement donors with male preponderance. In all the markers tested there was increased prevalence of TTI among the replacement donors as compared to voluntary donors. Conclusion: By implementing strict donor criteria and using sensitive screening tests, it may be possible to reduce the incidence of TTI in the Indian scenario.http://www.njlm.net/articles/PDF/2000/7645_E(_)_F(H)_Reformatted_PF1(PrH)_PFA(KH)_OLF.pdftransfusion transmitted infectionsnucleic acid testingblood donation |
| spellingShingle | Apra Kalra Parminder Kaur Gill Gopal Dutt Uniya How Safe is Blood? A 5 Year Retrospective Study National Journal of Laboratory Medicine transfusion transmitted infections nucleic acid testing blood donation |
| title | How Safe is Blood? A 5 Year Retrospective Study |
| title_full | How Safe is Blood? A 5 Year Retrospective Study |
| title_fullStr | How Safe is Blood? A 5 Year Retrospective Study |
| title_full_unstemmed | How Safe is Blood? A 5 Year Retrospective Study |
| title_short | How Safe is Blood? A 5 Year Retrospective Study |
| title_sort | how safe is blood a 5 year retrospective study |
| topic | transfusion transmitted infections nucleic acid testing blood donation |
| url | http://www.njlm.net/articles/PDF/2000/7645_E(_)_F(H)_Reformatted_PF1(PrH)_PFA(KH)_OLF.pdf |
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