Preparation and Bioevaluation of a Novel <sup>99m</sup>Tc-Labeled Glucose Derivative Containing Cyclohexane as a Promising Tumor Imaging Agent

Preparation and Bioevaluation of a Novel <sup>99m</sup>Tc-Labeled Glucose Derivative Containing Cyclohexane as a Promising Tumor Imaging Agent

To develop novel tumor imaging agents with high tumor uptake and excellent tumor/non-target ratios, a glucose derivative containing cyclohexane (CNMCHDG) was synthesized and labeled with Tc-99m. [<sup>99m</sup>Tc]Tc-CNMCHDG was prepared by a kit formulation that was straightforward to op...

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Detalles Bibliográficos
Autores principales: Junhong Feng, Xuran Zhang, Yuhao Jiang, Qing Ruan, Qianna Wang, Junbo Zhang
Formato: Artículo
Lenguaje:English
Publicado: MDPI AG 2023-04-01
Colección:Pharmaceuticals
Materias:
glucose derivative
cyclohexane
technetium-99m
SPECT
tumor
Acceso en línea:https://www.mdpi.com/1424-8247/16/4/612

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