Methyl 5-(4-hydroxy-3-methoxyphenyl)-2-(4-methoxybenzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate
In the title compound, C24H22N2O6S, a pyrimidine ring substituted with 4-hydroxy-3-methoxyphenyl is fused with a thiazole ring. The 4-hydroxy-3-methoxyphenyl group is positioned axially to the pyrimidine ring, making a dihedral angle 85.36 (7)°. The pyrimidine ring adopts...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
International Union of Crystallography
2011-12-01
|
| Series: | Acta Crystallographica Section E |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S1600536811048987 |
| _version_ | 1819293996756762624 |
|---|---|
| author | H. Nagarajaiah Noor Shahina Begum |
| author_facet | H. Nagarajaiah Noor Shahina Begum |
| author_sort | H. Nagarajaiah |
| collection | DOAJ |
| description | In the title compound, C24H22N2O6S, a pyrimidine ring substituted with 4-hydroxy-3-methoxyphenyl is fused with a thiazole ring. The 4-hydroxy-3-methoxyphenyl group is positioned axially to the pyrimidine ring, making a dihedral angle 85.36 (7)°. The pyrimidine ring adopts a twist boat conformation. In the crystal, O—H...N interactions result in a chain running along the b axis. The carbonyl O atom bonded to the thiazole ring is involved in two C—H...O hydrogen-bond interactions forming centrosymmetric dimers; the ten- and six-membered rings resulting from these interactions have R22(10) and R12(6) motifs, respectively. |
| first_indexed | 2024-12-24T04:19:18Z |
| format | Article |
| id | doaj.art-2d56ada208834bd785e5097bb049a1a7 |
| institution | Directory Open Access Journal |
| issn | 1600-5368 |
| language | English |
| last_indexed | 2024-12-24T04:19:18Z |
| publishDate | 2011-12-01 |
| publisher | International Union of Crystallography |
| record_format | Article |
| series | Acta Crystallographica Section E |
| spelling | doaj.art-2d56ada208834bd785e5097bb049a1a72022-12-21T17:15:51ZengInternational Union of CrystallographyActa Crystallographica Section E1600-53682011-12-016712o3444o344410.1107/S1600536811048987Methyl 5-(4-hydroxy-3-methoxyphenyl)-2-(4-methoxybenzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylateH. NagarajaiahNoor Shahina BegumIn the title compound, C24H22N2O6S, a pyrimidine ring substituted with 4-hydroxy-3-methoxyphenyl is fused with a thiazole ring. The 4-hydroxy-3-methoxyphenyl group is positioned axially to the pyrimidine ring, making a dihedral angle 85.36 (7)°. The pyrimidine ring adopts a twist boat conformation. In the crystal, O—H...N interactions result in a chain running along the b axis. The carbonyl O atom bonded to the thiazole ring is involved in two C—H...O hydrogen-bond interactions forming centrosymmetric dimers; the ten- and six-membered rings resulting from these interactions have R22(10) and R12(6) motifs, respectively.http://scripts.iucr.org/cgi-bin/paper?S1600536811048987 |
| spellingShingle | H. Nagarajaiah Noor Shahina Begum Methyl 5-(4-hydroxy-3-methoxyphenyl)-2-(4-methoxybenzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate Acta Crystallographica Section E |
| title | Methyl 5-(4-hydroxy-3-methoxyphenyl)-2-(4-methoxybenzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate |
| title_full | Methyl 5-(4-hydroxy-3-methoxyphenyl)-2-(4-methoxybenzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate |
| title_fullStr | Methyl 5-(4-hydroxy-3-methoxyphenyl)-2-(4-methoxybenzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate |
| title_full_unstemmed | Methyl 5-(4-hydroxy-3-methoxyphenyl)-2-(4-methoxybenzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate |
| title_short | Methyl 5-(4-hydroxy-3-methoxyphenyl)-2-(4-methoxybenzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate |
| title_sort | methyl 5 4 hydroxy 3 methoxyphenyl 2 4 methoxybenzylidene 7 methyl 3 oxo 2 3 dihydro 5h thiazolo 3 2 a pyrimidine 6 carboxylate |
| url | http://scripts.iucr.org/cgi-bin/paper?S1600536811048987 |
| work_keys_str_mv | AT hnagarajaiah methyl54hydroxy3methoxyphenyl24methoxybenzylidene7methyl3oxo23dihydro5hthiazolo32apyrimidine6carboxylate AT noorshahinabegum methyl54hydroxy3methoxyphenyl24methoxybenzylidene7methyl3oxo23dihydro5hthiazolo32apyrimidine6carboxylate |