Preparation and rheological properties of hydrogels based on N-succinyl chitosan and hyaluronic acid dialdehyde
Hydrogels based on both synthetic and natural polymers are currently used in agriculture, pharmaceuticals, medicine and other industries. The aim of this work was to determine the conditions for preparing chemically cross-linked hydrogels based on modified biopolymers – N-succinyl chitosan (NSCTS) a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-04-01
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| Series: | Polymer Testing |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0142941821000702 |
| _version_ | 1818728758487547904 |
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| author | Regina Rafailevna Vildanova Nataliya Nikolaevna Sigaeva Olga Sergeevna Kukovinets Sergey Viktorovich Kolesov |
| author_facet | Regina Rafailevna Vildanova Nataliya Nikolaevna Sigaeva Olga Sergeevna Kukovinets Sergey Viktorovich Kolesov |
| author_sort | Regina Rafailevna Vildanova |
| collection | DOAJ |
| description | Hydrogels based on both synthetic and natural polymers are currently used in agriculture, pharmaceuticals, medicine and other industries. The aim of this work was to determine the conditions for preparing chemically cross-linked hydrogels based on modified biopolymers – N-succinyl chitosan (NSCTS) and hyaluronic acid dialdehyde (HAD) with tunable rheological properties. The hydrogel systems have a yield point, the value of which increases with an increasing concentration of NSCTS. We have obtained the dependences of storage elastic modulus and loss modulus on the load exposure frequency at constant stress. The obtained values of the complex shear modulus increase with the growth of NSCTS molecular mass and concentration. Network parameters of hydrogels were evaluated by using rheology-based methods. We have identified the possibility of varying the ability of the obtained hydrogels to large reversible deformations, which makes it possible to use apply them in various situations. |
| first_indexed | 2024-12-17T22:35:05Z |
| format | Article |
| id | doaj.art-2d5a52c1b8ae449397fa82a83bb980ab |
| institution | Directory Open Access Journal |
| issn | 0142-9418 |
| language | English |
| last_indexed | 2024-12-17T22:35:05Z |
| publishDate | 2021-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Polymer Testing |
| spelling | doaj.art-2d5a52c1b8ae449397fa82a83bb980ab2022-12-21T21:30:06ZengElsevierPolymer Testing0142-94182021-04-0196107120Preparation and rheological properties of hydrogels based on N-succinyl chitosan and hyaluronic acid dialdehydeRegina Rafailevna Vildanova0Nataliya Nikolaevna Sigaeva1Olga Sergeevna Kukovinets2Sergey Viktorovich Kolesov3Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences, Ufa, 450054, Russia; Corresponding author.Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences, Ufa, 450054, Russia; Corresponding author.Bashkir State University, Ufa, 450017, RussiaUfa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences, Ufa, 450054, RussiaHydrogels based on both synthetic and natural polymers are currently used in agriculture, pharmaceuticals, medicine and other industries. The aim of this work was to determine the conditions for preparing chemically cross-linked hydrogels based on modified biopolymers – N-succinyl chitosan (NSCTS) and hyaluronic acid dialdehyde (HAD) with tunable rheological properties. The hydrogel systems have a yield point, the value of which increases with an increasing concentration of NSCTS. We have obtained the dependences of storage elastic modulus and loss modulus on the load exposure frequency at constant stress. The obtained values of the complex shear modulus increase with the growth of NSCTS molecular mass and concentration. Network parameters of hydrogels were evaluated by using rheology-based methods. We have identified the possibility of varying the ability of the obtained hydrogels to large reversible deformations, which makes it possible to use apply them in various situations.http://www.sciencedirect.com/science/article/pii/S0142941821000702HydrogelHyaluronic acidChitosanRheologyNetworkCross-linking |
| spellingShingle | Regina Rafailevna Vildanova Nataliya Nikolaevna Sigaeva Olga Sergeevna Kukovinets Sergey Viktorovich Kolesov Preparation and rheological properties of hydrogels based on N-succinyl chitosan and hyaluronic acid dialdehyde Polymer Testing Hydrogel Hyaluronic acid Chitosan Rheology Network Cross-linking |
| title | Preparation and rheological properties of hydrogels based on N-succinyl chitosan and hyaluronic acid dialdehyde |
| title_full | Preparation and rheological properties of hydrogels based on N-succinyl chitosan and hyaluronic acid dialdehyde |
| title_fullStr | Preparation and rheological properties of hydrogels based on N-succinyl chitosan and hyaluronic acid dialdehyde |
| title_full_unstemmed | Preparation and rheological properties of hydrogels based on N-succinyl chitosan and hyaluronic acid dialdehyde |
| title_short | Preparation and rheological properties of hydrogels based on N-succinyl chitosan and hyaluronic acid dialdehyde |
| title_sort | preparation and rheological properties of hydrogels based on n succinyl chitosan and hyaluronic acid dialdehyde |
| topic | Hydrogel Hyaluronic acid Chitosan Rheology Network Cross-linking |
| url | http://www.sciencedirect.com/science/article/pii/S0142941821000702 |
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