Bacterial translocation in colorectal cancer patients
Bacterial translocation is the penetration of intestinal bacteria through the intestinal mucosa into usually sterile tissues and internal organs. Commensal bacteria, despite their presence in the intestine in extremely large numbers, rarely cause local or systemic inflammation, because the unicellul...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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National Scientific Medical Center
2021-06-01
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| Series: | Ķazaķstannyṇ Klinikalyķ Medicinasy |
| Subjects: | |
| Online Access: | https://www.clinmedkaz.org/download/bacterial-translocation-in-colorectal-cancer-patients-10926.pdf |
| _version_ | 1818490814927470592 |
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| author | Alina Ogizbayeva Yermek Turgunov |
| author_facet | Alina Ogizbayeva Yermek Turgunov |
| author_sort | Alina Ogizbayeva |
| collection | DOAJ |
| description | Bacterial translocation is the penetration of intestinal bacteria through the intestinal mucosa into usually sterile tissues and internal organs. Commensal bacteria, despite their presence in the intestine in extremely large numbers, rarely cause local or systemic inflammation, because the unicellular epithelial layer of the intestinal mucosa prevents the migration of these bacteria from the intestine. For years, researchers have wondered how a single layer of intestinal epithelial cells can prevent microorganisms from entering the systemic circulation. Today, the phenomenon of bacterial translocation is considered as one of the main mechanisms of endotoxemia and systemic inflammatory response syndrome in various pathologies, including colorectal cancer and acute bowel obstruction. This narrative review is devoted to the search for factors promoting to bacterial translocation from the intestine in colorectal cancer and acute malignant bowel obstruction. <br />
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| first_indexed | 2024-12-10T17:22:21Z |
| format | Article |
| id | doaj.art-2d5d8e69c443462a9323feb7ec8512aa |
| institution | Directory Open Access Journal |
| issn | 1812-2892 2313-1519 |
| language | English |
| last_indexed | 2024-12-10T17:22:21Z |
| publishDate | 2021-06-01 |
| publisher | National Scientific Medical Center |
| record_format | Article |
| series | Ķazaķstannyṇ Klinikalyķ Medicinasy |
| spelling | doaj.art-2d5d8e69c443462a9323feb7ec8512aa2022-12-22T01:39:57ZengNational Scientific Medical CenterĶazaķstannyṇ Klinikalyķ Medicinasy1812-28922313-15192021-06-0118381310.23950/jcmk/10926Bacterial translocation in colorectal cancer patientsAlina Ogizbayeva0Yermek Turgunov1Department of Surgical Diseases, Karaganda Medical University, Karaganda city, Republic of KazakhstanDepartment of Surgical Diseases, Karaganda Medical University, Karaganda city, Republic of KazakhstanBacterial translocation is the penetration of intestinal bacteria through the intestinal mucosa into usually sterile tissues and internal organs. Commensal bacteria, despite their presence in the intestine in extremely large numbers, rarely cause local or systemic inflammation, because the unicellular epithelial layer of the intestinal mucosa prevents the migration of these bacteria from the intestine. For years, researchers have wondered how a single layer of intestinal epithelial cells can prevent microorganisms from entering the systemic circulation. Today, the phenomenon of bacterial translocation is considered as one of the main mechanisms of endotoxemia and systemic inflammatory response syndrome in various pathologies, including colorectal cancer and acute bowel obstruction. This narrative review is devoted to the search for factors promoting to bacterial translocation from the intestine in colorectal cancer and acute malignant bowel obstruction. <br /> <br /> <b> </b>https://www.clinmedkaz.org/download/bacterial-translocation-in-colorectal-cancer-patients-10926.pdfbacterial translocation; gut microbiota; intestinal barrier; colorectal cancer; bowel obstruction. |
| spellingShingle | Alina Ogizbayeva Yermek Turgunov Bacterial translocation in colorectal cancer patients Ķazaķstannyṇ Klinikalyķ Medicinasy bacterial translocation; gut microbiota; intestinal barrier; colorectal cancer; bowel obstruction. |
| title | Bacterial translocation in colorectal cancer patients |
| title_full | Bacterial translocation in colorectal cancer patients |
| title_fullStr | Bacterial translocation in colorectal cancer patients |
| title_full_unstemmed | Bacterial translocation in colorectal cancer patients |
| title_short | Bacterial translocation in colorectal cancer patients |
| title_sort | bacterial translocation in colorectal cancer patients |
| topic | bacterial translocation; gut microbiota; intestinal barrier; colorectal cancer; bowel obstruction. |
| url | https://www.clinmedkaz.org/download/bacterial-translocation-in-colorectal-cancer-patients-10926.pdf |
| work_keys_str_mv | AT alinaogizbayeva bacterialtranslocationincolorectalcancerpatients AT yermekturgunov bacterialtranslocationincolorectalcancerpatients |