The Humanization and Maturation of an Anti-PrPc Antibody

The Humanization and Maturation of an Anti-PrPc Antibody

The cellular prion protein (PrPc) is a cell surface glycoprotein that is highly expressed in a variety of cancer tissues in addition to the nervous system, and its elevated expression is correlated to poor prognosis in many cancer patients. Our team previously found that patients with colorectal can...

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Bibliographic Details
Main Authors:	Cheng Zhang, Fanlei Ran, Lei Du, Xiaohui Wang, Lei Liu, Jinming Liu, Quan Chen, Yang Cao, Lijun Bi, Haiying Hang
Format:	Article
Language:	English
Published:	MDPI AG 2024-02-01
Series:	Bioengineering
Subjects:	anti-PrPc antibody affinity maturation mammalian cell display humanization colorectal cancer
Online Access:	https://www.mdpi.com/2306-5354/11/3/242

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