The Humanization and Maturation of an Anti-PrPc Antibody
The cellular prion protein (PrPc) is a cell surface glycoprotein that is highly expressed in a variety of cancer tissues in addition to the nervous system, and its elevated expression is correlated to poor prognosis in many cancer patients. Our team previously found that patients with colorectal can...
Main Authors: | Cheng Zhang, Fanlei Ran, Lei Du, Xiaohui Wang, Lei Liu, Jinming Liu, Quan Chen, Yang Cao, Lijun Bi, Haiying Hang |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-02-01
|
Series: | Bioengineering |
Subjects: | |
Online Access: | https://www.mdpi.com/2306-5354/11/3/242 |
Similar Items
-
Tạo dòng, biểu hiện và tái gấp cuộn prion protein (PrPc) chuột dung hợp với GST
by: Trương Hà Minh Nhật, et al.
Published: (2019-10-01) -
HTLV-1 p12 modulates the levels of prion protein (PrPC) in CD4+ T cells
by: Isabela Silva De Castro, et al.
Published: (2023-08-01) -
El silenciamiento de la proteína priónica celular (PrPC) mediante RNA de interferencia (siRNA) reduce la infección por HSV-1 y HSV-2 en células SK-SY5Y
by: Elizabeth Ortega-Soto, et al.
Published: (2018-05-01) -
Deletion of <i>Kif5c</i> Does Not Alter Prion Disease Tempo or Spread in Mouse Brain
by: Brent Race, et al.
Published: (2021-07-01) -
The Role of Cellular Prion Protein in Glioma Tumorigenesis Could Be through the Autophagic Mechanisms: A Narrative Review
by: Daniele Armocida, et al.
Published: (2023-01-01)