Serum cytokine and chemokine profiles of patients with confirmed bacterial and viral meningitis
Introduction: Cerebrospinal fluid (CSF) cytokines and chemokines have been reported by several studies as useful markers to discriminate bacterial and viral meningitis (BM and VM). This study aimed to investigate if serum cytokine and chemokine profiles could also differentiate BM from VM, thus circ...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2023-10-01
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| Series: | Romanian Journal of Laboratory Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/rrlm-2023-0023 |
| _version_ | 1797646293751824384 |
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| author | Caragheorgheopol Ramona Țucureanu Cătălin Lazăr Veronica Caraș Iuliana |
| author_facet | Caragheorgheopol Ramona Țucureanu Cătălin Lazăr Veronica Caraș Iuliana |
| author_sort | Caragheorgheopol Ramona |
| collection | DOAJ |
| description | Introduction: Cerebrospinal fluid (CSF) cytokines and chemokines have been reported by several studies as useful markers to discriminate bacterial and viral meningitis (BM and VM). This study aimed to investigate if serum cytokine and chemokine profiles could also differentiate BM from VM, thus circumventing the need for an invasive lumbar puncture. |
| first_indexed | 2024-03-11T14:59:31Z |
| format | Article |
| id | doaj.art-2d5fc1082113480a94c6d14f75cdb87c |
| institution | Directory Open Access Journal |
| issn | 2284-5623 |
| language | English |
| last_indexed | 2024-03-11T14:59:31Z |
| publishDate | 2023-10-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Romanian Journal of Laboratory Medicine |
| spelling | doaj.art-2d5fc1082113480a94c6d14f75cdb87c2023-10-30T07:59:49ZengSciendoRomanian Journal of Laboratory Medicine2284-56232023-10-0131431532410.2478/rrlm-2023-0023Serum cytokine and chemokine profiles of patients with confirmed bacterial and viral meningitisCaragheorgheopol Ramona0Țucureanu Cătălin1Lazăr Veronica2Caraș Iuliana31Immunology Laboratory, “Cantacuzino” N.M.M.I.R.D., Bucharest, Romania1Immunology Laboratory, “Cantacuzino” N.M.M.I.R.D., Bucharest, Romania2Microbiology and Immunology Department, University of Bucharest, Faculty of Biology, Romania1Immunology Laboratory, “Cantacuzino” N.M.M.I.R.D., Bucharest, RomaniaIntroduction: Cerebrospinal fluid (CSF) cytokines and chemokines have been reported by several studies as useful markers to discriminate bacterial and viral meningitis (BM and VM). This study aimed to investigate if serum cytokine and chemokine profiles could also differentiate BM from VM, thus circumventing the need for an invasive lumbar puncture.https://doi.org/10.2478/rrlm-2023-0023machine learningrandom forestmeningitis diagnosisdifferential cytokine patternserum cytokines chemokines |
| spellingShingle | Caragheorgheopol Ramona Țucureanu Cătălin Lazăr Veronica Caraș Iuliana Serum cytokine and chemokine profiles of patients with confirmed bacterial and viral meningitis Romanian Journal of Laboratory Medicine machine learning random forest meningitis diagnosis differential cytokine pattern serum cytokines chemokines |
| title | Serum cytokine and chemokine profiles of patients with confirmed bacterial and viral meningitis |
| title_full | Serum cytokine and chemokine profiles of patients with confirmed bacterial and viral meningitis |
| title_fullStr | Serum cytokine and chemokine profiles of patients with confirmed bacterial and viral meningitis |
| title_full_unstemmed | Serum cytokine and chemokine profiles of patients with confirmed bacterial and viral meningitis |
| title_short | Serum cytokine and chemokine profiles of patients with confirmed bacterial and viral meningitis |
| title_sort | serum cytokine and chemokine profiles of patients with confirmed bacterial and viral meningitis |
| topic | machine learning random forest meningitis diagnosis differential cytokine pattern serum cytokines chemokines |
| url | https://doi.org/10.2478/rrlm-2023-0023 |
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